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高分辨率胸部CT在婴儿期神经内分泌细胞增生症诊断中的作用——一种罕见的小儿间质性肺疾病形式。

The role of high-resolution chest CT in the diagnosis of neuroendocrine cell hyperplasia of infancy - A rare form of pediatric interstitial lung disease.

作者信息

Lee Julia, Sanchez Thomas Ray, Zhang Yanhong, Jhawar Sanjay

机构信息

Department of Pediatrics, University of California, Davis, Sacramento, CA, USA.

Department of Radiology, From the Division of Pediatric Radiology, University of California, Davis Medical Center Children's Hospital, 4860 Y St., Suite 3100 ACC, Sacramento, CA, 95817, USA.

出版信息

Respir Med Case Rep. 2015 Sep 6;16:101-3. doi: 10.1016/j.rmcr.2015.09.001. eCollection 2015.

Abstract

Interstitial lung disease (ILD) is rare in infancy or early childhood. Differentiating between the different types of ILD is important for reasons of treatment, monitoring of clinical course and prognosis. We present a case of a 5-month old female with tachypnea and hypoxemia. The clinical suspicion of neuroendocrine cell hyperplasia of infancy (NEHI) was confirmed by high-resolution chest CT and subsequent lung biopsy. We conclude that high-resolution chest CT has characteristics findings that can be used as a non-invasive test to support the clinical diagnosis of neuroendocrine cell hyperplasia of infancy.

摘要

间质性肺疾病(ILD)在婴儿期或幼儿期较为罕见。区分不同类型的ILD对于治疗、临床病程监测及预后判断都很重要。我们报告一例5个月大的患呼吸急促和低氧血症的女性病例。高分辨率胸部CT及后续肺活检证实了临床对婴儿期神经内分泌细胞增生症(NEHI)的怀疑。我们得出结论,高分辨率胸部CT具有特征性表现,可作为一种非侵入性检查来支持婴儿期神经内分泌细胞增生症的临床诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e80/4681975/20c37d823e4f/gr1.jpg

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