Deterding Robin R
Pediatr Allergy Immunol Pulmonol. 2010 Mar;23(1):25-31. doi: 10.1089/ped.2010.0011.
Though interstitial lung disease (ILD) can occur at any age in children, disorders more common in infancy and young children have received increased attention as an important group that is disproportionally affected, linked to lung development and lung injury, and represents disorders not seen in adult ILD. Identifying those children with potential children's ILD (chILD) and establishing a specific chILD diagnosis has evolved and is critical for pediatric pulmonologists, neonatologists, radiologists, and pathologists to recognize. Specific disorders more common in infancy include diffuse developmental disorders, growth abnormalities, pulmonary interstitial glycogenosis, neuroendocrine cell hyperplasia of infancy, and surfactant mutation dysfunction mutations. The presentation, evaluation, treatment, and clinical course are discussed for each of these specific disorders and other categories less common in infants and young children are briefly mentioned. Resources for physicians and families are also reviewed.
虽然间质性肺病（ILD）可发生于儿童的任何年龄段，但在婴儿和幼儿中更常见的疾病作为一个受到不成比例影响的重要群体，已受到越来越多的关注，这些疾病与肺发育和肺损伤有关，并且代表了成人ILD中未见的疾病。识别那些患有潜在儿童ILD（chILD）的儿童并建立特定的chILD诊断已经发展起来，对于儿科肺病学家、新生儿科医生、放射科医生和病理学家来说，认识到这一点至关重要。在婴儿期更常见的特定疾病包括弥漫性发育障碍、生长异常、肺间质糖原沉积症、婴儿期神经内分泌细胞增生以及表面活性剂突变功能障碍突变。本文讨论了这些特定疾病中的每一种的表现、评估、治疗和临床过程，并简要提及了在婴儿和幼儿中不太常见的其他类别。还对医生和家庭的资源进行了综述。
