青少年肌阵挛癫痫患者的实践诱发癫痫发作：脑磁图-脑电图联合记录研究
Praxis-induced seizures in a patient with juvenile myoclonic epilepsy: MEG-EEG coregistration study.
作者信息
de León Sira Carrasco-García, Niso Guiomar, Canuet Leonidas, Burriel-Lobo Laura, Maestú Fernando, Rodríguez-Magariños María Gudín
机构信息
Department of Neurology, Teaching General Hospital, Ciudad Real, Spain.
Center for Biomedical Technology, Technical University of Madrid, Madrid, Spain; McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, Canada.
出版信息
Epilepsy Behav Case Rep. 2015 Nov 4;5:1-5. doi: 10.1016/j.ebcr.2015.10.002. eCollection 2016.
PURPOSE
Juvenile myoclonic epilepsy (JME) is one of the most common generalized idiopathic epilepsies of childhood and adolescence. In some patients with JME, mathematical calculus and praxis may induce myoclonic seizures.
METHODS
A reflex myoclonic seizure was recorded by simultaneous magnetoencephalography (MEG) and electroencephalography (EEG) when a generalized spike-wave synchronous pattern at 3 Hz was observed.
RESULTS
Source reconstruction localized the epileptogenic area to the right premotor frontal cortex.
CONCLUSIONS
The present study demonstrates that the origin of epileptiform activity in JME can be localized in brain areas associated with the premotor frontal cortex.
目的
青少年肌阵挛癫痫（JME）是儿童和青少年时期最常见的全身性特发性癫痫之一。在一些JME患者中，数学运算和动作执行可能会诱发肌阵挛发作。
方法
当观察到3Hz的全身性棘波-慢波同步模式时，通过同步脑磁图（MEG）和脑电图（EEG）记录反射性肌阵挛发作。
结果
源重建将致痫区域定位到右侧运动前区额叶皮质。
结论
本研究表明，JME中癫痫样活动的起源可定位在与运动前区额叶皮质相关的脑区。
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