Tatum William O, DiCiaccio Benedetto, Kipta Joseph A, Yelvington Kirsten H, Stein Michael A
*Department of Neurology, Mayo Clinic College of Medicine, Mayo Clinic in Florida, Jacksonville, Florida, U.S.A.; †University of Florida, Gainesville, Florida, U.S.A.; and ‡Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, U.S.A.
J Clin Neurophysiol. 2016 Aug;33(4):359-66. doi: 10.1097/WNP.0000000000000250.
We report a unique EEG phenomenon in patients with paroxysmal neurological events undergoing video EEG monitoring.
Two epilepsy centers analyzed the interictal scalp EEG in patients using personal electronic devices during epilepsy monitoring. The texting rhythm (TR) was defined as a reproducible, stimulus-evoked, generalized frontocentral monomorphic burst of 5-6 Hz theta consistently induced by active text messaging. An independent prospective and retrospective cohort was analyzed and compared from two sites in Florida and Illinois. We assessed age, gender, diagnosis, epilepsy classification, MRI, and EEG to compare patients with a TR. Analysis was performed with statistical significance set at P < 0.05.
We identified 24 of 98 evaluable patients with a TR in a prospective arm at one center and 7 of 31 patients in a retrospective arm at another totaling 31/129 (24.0%). The waveform prevalence was similar at both centers independent of location. TR was highly specific to active texting. A similar waveform during independent cognitive, speech or language, motor activation and audio cellular telephone use was absent (P < 0.0001). It appeared to be increased in patients with epilepsy in one cohort (P = 0.03) and generalized seizures in the other (P = 0.025). Age, gender, epilepsy type, MRI results, and EEG lateralization in patients with focal epileptic seizures did not bear a relationship to the presence of a TR in either arm of the study (P = NS).
The TR is a novel waveform time-locked to text messaging and associated with active use of smartphones. Electroencephalographers should be aware of the TR to separate it from an abnormality in patients undergoing video EEG monitoring. Larger sample sizes and additional research may help define the significance of this unique cognitive-visual-cognitive-motor network that is technology-related and task-specific with implications in communication research and transportation safety.
我们报告了在接受视频脑电图监测的阵发性神经事件患者中出现的一种独特的脑电图现象。
两个癫痫中心在癫痫监测期间分析了使用个人电子设备的患者的发作间期头皮脑电图。短信节奏（TR）被定义为一种可重复的、刺激诱发的、由活跃短信持续诱发的5-6赫兹θ波的全身性额中央单形爆发。对来自佛罗里达州和伊利诺伊州两个地点的独立前瞻性和回顾性队列进行了分析和比较。我们评估了年龄、性别、诊断、癫痫分类、磁共振成像（MRI）和脑电图，以比较有TR的患者。分析时设定统计学显著性为P<0.05。
在一个中心的前瞻性队列中，98名可评估患者中有24名有TR，在另一个中心的回顾性队列中，31名患者中有7名有TR，总计31/129（24.0%）。两个中心的波形发生率相似，与地点无关。TR对活跃短信高度特异。在独立的认知、言语或语言、运动激活和使用音频手机时未出现类似波形（P<0.0001）。在一个队列中，癫痫患者中其似乎有所增加（P=0.03），在另一个队列中，全身性发作患者中也有所增加（P=0.025）。局灶性癫痫发作患者的年龄、性别、癫痫类型、MRI结果和脑电图定位在研究的任何一个队列中与TR的存在均无关联（P=无显著性差异）。
TR是一种与短信相关的新型波形，与智能手机的活跃使用有关。脑电图检查人员应注意TR，以便在接受视频脑电图监测的患者中将其与异常情况区分开来。更大的样本量和更多的研究可能有助于确定这种与技术相关且特定于任务的独特认知-视觉-认知-运动网络的意义，这对通信研究和交通安全有影响。
