Leonardi C, Vellucci R, Mammucari M, Fanelli G
Drug Addiction Department, ASL RMC, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2015 Dec;19(24):4898-905.
Chronic pain is one of the most common complaints for people seeking medical care, with a series of potential detrimental effects on the individual and his social texture. Despite the heavy impact of chronic pain on patients' quality of life, epidemiological data suggest that chronic pain is often untreated or undertreated. An accurate diagnostic flow and appropriate treatment should be considered as key factors for optimal management of patients with chronic pain. Opioids are recommended for treatment of chronic cancer pain (CCP) and chronic non-cancer pain (CNCP) in guidelines and can safely and effectively relieve pain in a number of patients with chronic pain. Conversely, fears of addiction and adverse events could result in ineffective pain management. Recent epidemiological and clinical data demonstrate that only low percentages of patients treated with opioids for chronic pain have a risk to develop addiction, with a prevalence rate similar to that observed in the general population.
Despite the iatrogenic risk can be considered as low, validated tools for the early identification of patients at higher risk of addiction can help health professionals in the overall management of chronic pain.
Due to the increasing relevance of primary care physicians in chronic pain management, we propose a 28-item questionnaire to validate specifically conceived for GPs' and aimed at the preliminary evaluation of the risk of addiction in patients with chronic pain.
慢性疼痛是寻求医疗护理的人群中最常见的主诉之一,对个人及其社会结构有一系列潜在的不利影响。尽管慢性疼痛对患者的生活质量有重大影响,但流行病学数据表明,慢性疼痛往往未得到治疗或治疗不足。准确的诊断流程和适当的治疗应被视为慢性疼痛患者最佳管理的关键因素。在指南中,阿片类药物被推荐用于治疗慢性癌痛(CCP)和慢性非癌痛(CNCP),并且可以安全有效地缓解许多慢性疼痛患者的疼痛。相反,对成瘾和不良事件的担忧可能导致疼痛管理无效。最近的流行病学和临床数据表明,接受阿片类药物治疗慢性疼痛的患者中,只有低比例的人有成瘾风险,其患病率与普通人群中观察到的相似。
尽管医源性风险可被视为较低,但用于早期识别成瘾风险较高患者的经过验证的工具可帮助卫生专业人员进行慢性疼痛的整体管理。
由于初级保健医生在慢性疼痛管理中的相关性日益增加,我们提出了一份28项问卷,专门为全科医生设计并旨在对慢性疼痛患者的成瘾风险进行初步评估。