Senol Taylan, Kahramanoglu Ilker, Muezzinoglu Bahar, Yucesoy Izzet
Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Kocaeli University Medical School, Kocaeli, Turkey.
Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Istanbul University Cerrahpasa Medical School, Istanbul, Turkey.
Int J Surg Case Rep. 2016;19:109-11. doi: 10.1016/j.ijscr.2015.12.042. Epub 2015 Dec 28.
Uterine leiomyosarcoma is a rare uterine malignancy. Most of the patients lack symptoms or present with a rapidly enlarging pelvic mass.
We report on a very large leiomyosarcoma in a woman presenting with a 3 months history of rapidly growing adominal mass and fatigue. Laparotomy was performed and diagnosis was confirmed by pathologic and histologic analysis. Patient refused chemotherapy after surgery and died from recurrence at 4th postoperative month.
Uterine leiomyosarcomas may follow a rapid clinical course with a doubling time of four weeks. There is no reliable method to distinguish uterine sarcoma from benign leiomyomas preoperatively.
This case represents the largest leiomyosarcoma reported in the literature.
子宫平滑肌肉瘤是一种罕见的子宫恶性肿瘤。大多数患者没有症状,或表现为盆腔肿块迅速增大。
我们报告一例非常大的平滑肌肉瘤,患者为一名女性,有3个月快速增大的腹部肿块和疲劳病史。进行了剖腹手术,病理和组织学分析证实了诊断。患者术后拒绝化疗,术后第4个月死于复发。
子宫平滑肌肉瘤的临床病程可能很快,倍增时间为4周。术前没有可靠的方法将子宫肉瘤与良性平滑肌瘤区分开来。
本病例是文献报道中最大的平滑肌肉瘤。