Vellanki Venkata Sujatha, Rao Meghana, Sunkavalli Chinna Babu, Chinamotu Rao N, Kaja Shailaja
Department of Obstetrics and Gynaecology, Kamineni Institute of Medical Sciences Sreepuram, Narketpally, Nalgonda - 508254, Andhra Pradesh, India.
J Med Case Rep. 2010 Jul 22;4:222. doi: 10.1186/1752-1947-4-222.
Malignant change in a leiomyoma or uterine fibroid is termed leiomyosarcoma. It arises from smooth muscle of the uterus and is a rare tumor that accounts for 2% to 5% of all uterine malignancies. Very few cases are reported in the literature. Our patient did not have any history of genital bleeding, which is the usual presentation in uterine sarcoma. We report an original case report of an unusual presentation of this rare tumor arising from the uterus.
A 40-year-old nulliparous woman of South Indian origin presented with a mass in her abdomen for one year with a rapid increase in size over the previous three months. Tumor marker CA-125 was raised, and a computed tomography scan showed a mass arising from the pelvis. An exploratory laparotomy was performed and the histopathology report confirmed the diagnosis of uterine leiomyosarcoma.
Because of their rarity, uterine sarcomas are not suitable for screening. Diagnosis is by histopathologic examination and surgery is the only treatment. The prognosis for women with uterine sarcoma primarily depends on the extent of disease at the time of diagnosis and the mitotic index.
平滑肌瘤或子宫肌瘤发生恶性变称为平滑肌肉瘤。它起源于子宫平滑肌，是一种罕见肿瘤，占所有子宫恶性肿瘤的2%至5%。文献报道的病例极少。我们的患者没有任何生殖器出血史，而这是子宫肉瘤的常见表现。我们报告一例源于子宫的这种罕见肿瘤的不寻常表现的原始病例。
一名40岁未生育的南印度裔女性，腹部肿物已有一年，在前三个月内肿物大小迅速增大。肿瘤标志物CA - 125升高，计算机断层扫描显示盆腔有一肿物。进行了剖腹探查术，组织病理学报告确诊为子宫平滑肌肉瘤。
由于子宫肉瘤罕见，不适合进行筛查。诊断依靠组织病理学检查，手术是唯一的治疗方法。子宫肉瘤女性患者的预后主要取决于诊断时疾病的范围和有丝分裂指数。
