Baron Kelly Glazer, Reid Kathryn J, Malkani Roneil G, Kang Joseph, Zee Phyllis C
a Department of Neurology , Northwestern University , Chicago , Illinois.
b Feinberg School of Medicine , Northwestern University , Chicago , Illinois.
Behav Sleep Med. 2017 Mar-Apr;15(2):144-157. doi: 10.1080/15402002.2015.1120200. Epub 2016 Jan 8.
Sleep variability has been linked to poor subjective sleep quality, but few studies have investigated effects on physical health. In this study, we evaluated cross sectional associations and change over time in objective sleep variability of adults with insomnia and short sleep duration who were participating in a non-pharmacologic intervention study. Results indicated greater variability in objective sleep measures were associated with poorer subjective sleep quality (p < 0.05). Higher sleep duration variability was associated with higher HbA1c (p < 0.01) and sleep onset time variability was associated with higher BMI (p < 0.05). Sleep efficiency and WASO variability decreased with intervention (p < 0.05). These results indicate that objective sleep variability may be an important feature for the assessment of insomnia outcomes.
睡眠变异性与较差的主观睡眠质量有关,但很少有研究调查其对身体健康的影响。在本研究中,我们评估了参与非药物干预研究的失眠和睡眠时长较短的成年人客观睡眠变异性的横断面关联以及随时间的变化。结果表明,客观睡眠指标的较大变异性与较差的主观睡眠质量相关(p < 0.05)。较高的睡眠时长变异性与较高的糖化血红蛋白水平相关(p < 0.01),而睡眠起始时间变异性与较高的体重指数相关(p < 0.05)。随着干预,睡眠效率和觉醒时间变异性降低(p < 0.05)。这些结果表明,客观睡眠变异性可能是评估失眠结局的一个重要特征。