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有和没有失眠症状的2型糖尿病患者的睡眠效率和总睡眠时间

Sleep Efficiency and Total Sleep Time in Individuals with Type 2 Diabetes with and without Insomnia Symptoms.

作者信息

Alshehri Mohammed M, Alkathiry Abdulaziz A, Alenazi Aqeel M, Alothman Shaima A, Rucker Jason L, Phadnis Milind A, Miles John M, Kluding Patricia M, Siengsukon Catherine F

机构信息

Physical Therapy and Rehabilitation Science Department, University of Kansas Medical Center, Kansas City, Kansas, USA.

Physical Therapy Department, Jazan University, Jazan City, Southern Region, Saudi Arabia.

出版信息

Sleep Disord. 2020 Jul 17;2020:5950375. doi: 10.1155/2020/5950375. eCollection 2020.

Abstract

There is increasing awareness of the high prevalence of insomnia symptoms in individuals with type 2 diabetes (T2D). Past studies have established the importance of measuring sleep parameters using measures of central tendency and variability. Additionally, subjective and objective methods involve different constructs due to the discrepancies between the two approaches. Therefore, this study is aimed at comparing the averages of sleep parameters in individuals with T2D with and without insomnia symptoms and comparing the variability of sleep parameters in these individuals. This study assessed the between-group differences in the averages and variability of sleep efficiency (SE) and total sleep time (TST) of 59 participants with T2D with and without insomnia symptoms. Actigraph measurements and sleep diaries were used to assess sleep parameter averages and variabilities calculated by the coefficient of variation across 7 nights. Mann-Whitney tests were utilized to compare group differences in the outcomes. Validated instruments were used to assess the symptoms of depression, anxiety, and pain as covariates. Objective SE was found to be statistically lower on average (85.98 ± 4.29) and highly variable (5.88 ± 2.57) for patients with T2D and insomnia symptoms than in those with T2D only (90.23 ± 6.44 and 3.82 ± 2.05, respectively). The subjective average and variability of SE were also worse in patients with T2D and insomnia symptoms, with symptoms of depression, anxiety, and pain potentially playing a role in this difference. TST did not significantly differ between the groups on averages or in variability even after controlling for age and symptoms of depression, anxiety, and pain. Future studies are needed to investigate the underlying mechanisms of worse averages and variability of SE in individuals with T2D and insomnia symptoms. Additionally, prompting the associated risk factors of insomnia symptoms in individuals with T2D might be warranted.

摘要

2型糖尿病(T2D)患者中失眠症状的高患病率正日益受到关注。过去的研究已经确立了使用集中趋势和变异性测量方法来测量睡眠参数的重要性。此外,由于主观和客观方法之间存在差异,它们涉及不同的结构。因此,本研究旨在比较有和没有失眠症状的T2D患者的睡眠参数平均值,并比较这些患者睡眠参数的变异性。本研究评估了59名有和没有失眠症状的T2D参与者在睡眠效率(SE)和总睡眠时间(TST)的平均值和变异性方面的组间差异。采用活动记录仪测量和睡眠日记来评估通过7晚变异系数计算出的睡眠参数平均值和变异性。使用曼-惠特尼检验来比较结果中的组间差异。使用经过验证的工具来评估抑郁、焦虑和疼痛症状作为协变量。结果发现,患有T2D和失眠症状的患者的客观SE平均在统计学上较低(85.98±4.29)且高度可变(5.88±2.57),而仅患有T2D的患者分别为(90.23±6.44和3.82±2.05)。患有T2D和失眠症状的患者在SE的主观平均值和变异性方面也较差,抑郁、焦虑和疼痛症状可能在这种差异中起作用。即使在控制了年龄以及抑郁、焦虑和疼痛症状后,两组在TST的平均值或变异性方面也没有显著差异。未来需要进行研究以调查患有T2D和失眠症状的个体中SE平均值和变异性较差的潜在机制。此外,可能有必要探究T2D患者失眠症状的相关危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6257/7382760/123d8fa43934/SD2020-5950375.001.jpg

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