Shcherbakov A M, Lur'e A A
Med Parazitol (Mosk). 1989 May-Jun(3):46-9.
Increasing mebendazole bioavailability is one of the most important problems to be solved in echinococcosis chemotherapy. The method of mebendazole administration with sunflower oil, elaborated by the authors, serves to this purpose: drug concentration exceeding the minimal effective one was attained in 86% patients treated with mebendazole and sunflower oil and only in 40% patients treated with the drug alone.
提高甲苯达唑的生物利用度是棘球蚴病化疗中有待解决的最重要问题之一。作者所阐述的甲苯达唑与葵花籽油联合给药方法即为此目的：在接受甲苯达唑与葵花籽油治疗的患者中，86%的患者药物浓度超过最低有效浓度，而单独使用该药物治疗的患者中这一比例仅为40%。
