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一家综合医院25年的肾脏替代治疗

[25 years of kidney replacement treatment at a general hospital].

作者信息

Gerlag P G, Berenschot H, Deckers P F

出版信息

Ned Tijdschr Geneeskd. 1989 Jul 1;133(26):1318-22.

PMID:2674733
Abstract

Between February 1963 and January 1988, 174 patients were treated for acute and 307 for chronic renal failure by dialysis in the St. Joseph Hospital Eindhoven, a general hospital. Sixty-two per cent of the patients treated for acute renal failure had tubular necrosis as a cause. In the patients treated for end-stage renal disease the median age of the dialysis population increased from 37 to 62 years. Vascular renal disease and diabetes mellitus were more frequent during the last ten years. Because of the inflow of older people, the outflow by death increased strongly, while the outflow by transplantation remained stable during the last 15 years. Due to an active transplantation policy together with haemodialysis at home and CAPD, 66% of the total now living patient population could be discharged from the dialysis department. Infection and cardiovascular accidents were the major causes of morbidity and mortality among the dialysis and transplant patients. Overall survival curves of all treated patients showed a 5-year survival of 60% and a 10-year survival of 42%.

摘要

1963年2月至1988年1月期间,位于埃因霍温的一家综合医院——圣约瑟夫医院,对174例急性肾衰竭患者和307例慢性肾衰竭患者进行了透析治疗。因急性肾衰竭接受治疗的患者中有62%的病因是肾小管坏死。在接受终末期肾病治疗的患者中,透析人群的年龄中位数从37岁增至62岁。过去十年间,血管性肾病和糖尿病更为常见。由于老年患者的流入,死亡流出量大幅增加,而移植流出量在过去15年中保持稳定。由于积极的移植政策以及家庭血液透析和持续性不卧床腹膜透析,目前仍在世的患者中66%可以从透析科出院。感染和心血管意外是透析和移植患者发病和死亡的主要原因。所有接受治疗患者的总体生存曲线显示,5年生存率为60%,10年生存率为42%。

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