Kim Bohyun, Lee Chang Kyung, Seo Nieun, Lee Seung Soo, Kim Jeong Kon, Choi Yoonseok, Woo Dong-Cheol, Kim In Seong, Nickel Dominik, Kim Kyung Won
Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro, Seoul, Republic of Korea; Department of Radiology, Ajou University School of Medicine, 165 Worldcup-ro, Suwon, Republic of Korea.
Bioimaging Center, Asan Institute for Life Sciences, Asan Medical Center, 88 Olympic-ro, Seoul, Republic of Korea.
Magn Reson Imaging. 2016 Jun;34(5):638-44. doi: 10.1016/j.mri.2015.11.011. Epub 2015 Dec 31.
To validate radial acquisition of volumetric interpolated breath hold examination (Radial-VIBE) and the controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA-VIBE) sequences for dynamic contrast-enhanced MRI (DCE-MRI) by comparing them to conventional VIBE sequence using a phantom.
On a DCE-MRI phantom containing various concentrations of NiCl2 solutions, six minutes of dynamic series and T1 mapping with variable flip angle methods were acquired using conventional VIBE, Radial-VIBE, and CAIPIRINHA-VIBE sequences on 3.0-T scanners. Signal stability and signal linearity were tested for dynamic series and the precision of R1 values were tested for T1 mapping series. The scans were repeatedly performed at two weeks and three months to test repeatability/reproducibility, assessed by within-subject coefficient of variation (WSCV).
Signal stability over six minutes was excellent in all three sequences. Regarding the signal linearity, CAIPIRINHA-VIBE demonstrated the highest linear correlation (r=0.963), followed by conventional VIBE (r=0.959) and Radial-VIBE (r=0.953). Regarding the R1 precision, CAIPIRINHA-VIBE (r=0.985) was the most accurate, followed by conventional VIBE (r=0.861) and Radial-VIBE (r=0.442). CAIPIRINHA-VIBE showed excellent repeatability/reproducibility (WSCV, 1.79-6.71%) compared with Radial-VIBE (WSCV, 2.04-67.2%) and conventional VIBE (WSCV, 3.4-31.9%).
In terms of signal stability, signal linearity, R1 precision, and repeatability/reproducibility, CAIPIRINHA-VIBE demonstrated outstanding performance for DCE-MRI compared with Radial-VIBE and conventional VIBE.
通过使用体模将容积内插屏气检查的径向采集序列（Radial-VIBE）和并行成像中的可控自校准部分并行采集技术高加速序列（CAIPIRINHA-VIBE）与传统VIBE序列进行比较，以验证其在动态对比增强磁共振成像（DCE-MRI）中的效果。
在含有不同浓度氯化镍溶液的DCE-MRI体模上，使用3.0-T扫描仪，通过传统VIBE序列、Radial-VIBE序列和CAIPIRINHA-VIBE序列采集6分钟的动态序列以及采用可变翻转角方法进行T1映射。对动态序列测试信号稳定性和信号线性，对T1映射序列测试R1值的精度。在两周和三个月时重复扫描以测试重复性/再现性，通过受试者内变异系数（WSCV）进行评估。
所有三个序列在6分钟内的信号稳定性都非常好。在信号线性方面，CAIPIRINHA-VIBE表现出最高的线性相关性（r = 0.963），其次是传统VIBE（r = 0.959）和Radial-VIBE（r = 0.953）。在R1精度方面，CAIPIRINHA-VIBE（r = 0.985）最准确，其次是传统VIBE（r = 0.861）和Radial-VIBE（r = 0.442）。与Radial-VIBE（WSCV，范围2.04 - 67.2%）和传统VIBE（WSCV，范围3.4 - 31.9%）相比，CAIPIRINHA-VIBE显示出优异的重复性/再现性（WSCV，范围1.79 - 6.71%）。
在信号稳定性、信号线性、R1精度以及重复性/再现性方面，与Radial-VIBE和传统VIBE相比，CAIPIRINHA-VIBE在DCE-MRI中表现出卓越的性能。
