Albrecht M H, Bodelle B, Varga-Szemes A, Dewes P, Bucher A M, Ball B D, De Cecco C N, Schoepf U J, Zhu X, Zangos S, Gruber-Rouh T, Wichmann J L, Lehnert T, Vogl T J
University Hospital Frankfurt, Department of Diagnostic and Interventional Radiology, Frankfurt,Germany; Medical University of South Carolina, Department of Radiology and Radiological Science, Charleston, SC, USA.
University Hospital Frankfurt, Department of Diagnostic and Interventional Radiology, Frankfurt,Germany.
Eur J Radiol. 2017 Jan;86:20-25. doi: 10.1016/j.ejrad.2016.10.025. Epub 2016 Oct 25.
To evaluate the impact of controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) volume interpolated breath-hold examination (VIBE) magnetic resonance imaging (MRI) technique on image quality, reader confidence, and inter-observer agreement for the assessment of focal liver lesions in comparison with the standard VIBE approach.
In this IRB-approved intra-individual comparison study, abdominal arterial and portal-venous contrast-enhanced MRI studies were retrospectively analyzed in 38 patients with malignant liver lesions. Each patient underwent both CAIPIRINHA and conventional VIBE 3T MRI within 3 months, showing stable disease. Images were evaluated using 5-point rating scales by two blinded radiologists with more than 20 and 5 years of experience in MRI, respectively. Readers scored dignity of liver lesions and assessed which liver segments were affected by malignancy (ranging from 1=definitely benign/not affected to 5=definitely malignant/affected by malignancy). Readers also rated overall image quality, sharpness of intrahepatic veins, and diagnostic confidence (ranging from 1=poor to 5=excellent).
Reviewers achieved a higher inter-observer reliability using CAIPIRINHA when they reported which liver segments were affected by malignancy compared to traditional VIBE series (κ=0.62 and 0.54, respectively, p<0.05). Similarly, CAIPIRINHA showed a slightly higher inter-rater agreement for the dignity of focal liver lesions versus the standard VIBE images (κ=0.50 and 0.49, respectively, p<0.05). CAIPIRINHA series also scored higher in comparison to standard VIBE sequences (mean scores: image quality, 4.2 and 3.5; sharpness of intrahepatic vessels, 3.8 and 3.2, respectively, p<0.05) for both reviewers and allowed for higher subjective diagnostic confidence (ratings, 3.8 and 3.2, respectively, p<0.05).
Compared to the standard VIBE approach, CAIPIRINHA VIBE technique provides improved image quality and sharpness of intrahepatic veins, as well as higher diagnostic confidence. Additionally, this technique allows for higher inter-observer agreement when reporting focal liver lesions for both dignity and allocation.
评估并行成像中控制混叠以实现更高加速（CAIPIRINHA）的容积内插屏气检查（VIBE）磁共振成像（MRI）技术与标准VIBE方法相比，对肝脏局灶性病变评估的图像质量、阅片者信心及观察者间一致性的影响。
在这项经机构审查委员会（IRB）批准的个体内比较研究中，对38例肝脏恶性病变患者的腹部动脉期和门静脉期对比增强MRI研究进行回顾性分析。每位患者在3个月内分别接受了CAIPIRINHA和传统VIBE 3T MRI检查，病情稳定。由两位分别具有超过20年和5年MRI经验的盲法放射科医生使用5分制评分量表对图像进行评估。阅片者对肝脏病变的特征进行评分，并评估哪些肝段受恶性肿瘤影响（范围从1 = 肯定为良性/未受影响到5 = 肯定为恶性/受恶性肿瘤影响）。阅片者还对整体图像质量、肝内静脉清晰度和诊断信心进行评分（范围从1 = 差到5 = 优）。
与传统VIBE序列相比，阅片者在报告哪些肝段受恶性肿瘤影响时，使用CAIPIRINHA时观察者间可靠性更高（κ分别为0.62和0.54，p < 0.05）。同样，与标准VIBE图像相比，CAIPIRINHA在肝脏局灶性病变特征方面的评分者间一致性略高（κ分别为0.50和0.49，p < 0.05）。与标准VIBE序列相比，CAIPIRINHA序列在两位阅片者的评分中也更高（平均评分：图像质量，4.2和3.5；肝内血管清晰度，3.8和3.2，p < 0.05），并具有更高的主观诊断信心（评分分别为3.8和3.2，p < 0.05）。
与标准VIBE方法相比，CAIPIRINHA VIBE技术可提高图像质量和肝内静脉清晰度，以及诊断信心。此外，该技术在报告肝脏局灶性病变的特征和分布时，观察者间一致性更高。
