Higer H P, Pedrosa P, Schuth M
Department of Magnetic Resonance Imaging, German Diagnostic Clinic, Wiesbaden, West Germany.
Neurosurg Rev. 1989;12(2):91-106. doi: 10.1007/BF01741480.
MR imaging of the brain has made tremendous progress during the last years. This technique is generally superior to computed tomography (CT) in brain tumors, due to its capability for direct imagining in various planes and its high tissue contrast. Moreover, the detectability and differentiation of extraaxial tumors, previously the domain of CT, has been improved with paramagnetic contrast agents (PCA). Although, the sensitivity of MRI for intracranial tumors is unchallenged, the specificity for such tumors is not remarcably greater than that of CT. Differentiation between high grade glioma, abscess and metastasis still requires biopsy for definitive diagnosis. Methods for improvement of specificity--tissue characterization--are currently being evaluated in a clinical setting. Further development in this field is necessary before such methods can be applied on a routine basis.
在过去几年中，脑部磁共振成像（MR成像）取得了巨大进展。由于该技术能够在多个平面进行直接成像且具有高组织对比度，因此在脑肿瘤方面通常优于计算机断层扫描（CT）。此外，顺磁性造影剂（PCA）提高了对轴外肿瘤的可检测性和鉴别能力，而轴外肿瘤此前一直是CT的检查范畴。虽然MRI对颅内肿瘤的敏感性无可争议，但其对此类肿瘤的特异性并不比CT显著更高。高级别胶质瘤、脓肿和转移瘤之间的鉴别仍需要活检以明确诊断。目前正在临床环境中评估提高特异性的方法——组织特征分析。在这些方法能够常规应用之前，该领域有必要进一步发展。
