Waaijers Susanne L, Parsons John R
National Institute for Public Health and the Environment (RIVM), Center for Safety of Substances and Products, P.O. Box 1, 3720 BA Bilthoven, The Netherlands.
Institute for Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam, P.O. Box 94240, 1092 GE Amsterdam, The Netherlands.
Curr Opin Biotechnol. 2016 Apr;38:14-23. doi: 10.1016/j.copbio.2015.12.005. Epub 2015 Dec 31.
Brominated flame retardants account for about 21% of the total production of flame retardants and many of these have been identified as persistent, bioaccumulative and toxic. Nevertheless, debromination of these chemicals under anaerobic conditions is well established, although this can increase their toxicity. Consequently, the production and use of these chemicals has been restricted and alternative products have been developed. Many of these are brominated compounds and share some of the disadvantages of the chemicals they are meant to replace. Therefore, other, nonbrominated, flame retardants such as organophosphorus compounds are also being used in increasing quantities, despite the fact that knowledge of their biodegradation and environmental fate is often lacking.
溴化阻燃剂约占阻燃剂总产量的21%，其中许多已被认定为具有持久性、生物累积性和毒性。然而，尽管这些化学物质在厌氧条件下的脱溴作用会增加其毒性，但这一过程已得到充分证实。因此，这些化学物质的生产和使用受到了限制，并已开发出替代产品。其中许多是溴化化合物，存在它们旨在取代的化学物质的一些缺点。因此，尽管通常缺乏对其生物降解和环境归宿的了解，但其他非溴化阻燃剂，如有机磷化合物的使用量也在不断增加。
