Leider A S, Jonker L A, Cook H E
Department of Diagnostic Sciences, University of the Pacific School of Dentistry, San Francisco, Calif.
Oral Surg Oral Med Oral Pathol. 1989 Aug;68(2):175-81. doi: 10.1016/0030-4220(89)90189-8.
Three cases of multicentric squamous odontogenic tumor, one of which was previously reported, are presented in three black siblings. A review of the literature indicates that 5 of the 26 previously recorded cases arose in multiple sites, but no evidence of familial history has been suggested. Although squamous odontogenic tumor has been described as a relatively rare, benign odontogenic neoplasm, the multicentric familial nature of our present cases suggests this represents either a reactive hyperplasia or hamartoma of residual odontogenic epithelium within the periodontal tissues. Management of previous cases has varied from simple curettage to maxillectomy with only one case of recurrence.
本文报告了3例多中心性鳞状牙源性肿瘤，其中1例曾有过报道，患者为3名黑人兄弟姐妹。文献回顾表明，之前记录的26例病例中有5例发生于多个部位，但未发现有家族病史的证据。尽管鳞状牙源性肿瘤被认为是一种相对罕见的良性牙源性肿瘤，但我们目前病例的多中心家族性特征提示，这可能代表牙周组织内残余牙源性上皮的反应性增生或错构瘤。之前病例的治疗方法各不相同，从单纯刮除术到上颌骨切除术，仅有1例复发。
