Parsons Philip J, Jones Daniel R, Padgham Alex C, Allen Lewis A T, Penkett Clive S, Green Robert A, White Andrew J P
Department of Chemistry, Imperial College London, South Kensington, London, SW7 2AZ, UK.
School of Chemistry, University of Southampton, Southampton, SO17 1BJ, UK.
Chemistry. 2016 Mar 14;22(12):3981-4. doi: 10.1002/chem.201504421. Epub 2016 Feb 11.
Pentasubstituted aromatic rings serve as templates for drug design and can be conveniently prepared by the thermolysis of suitably substituted alkynes under microwave conditions.
五取代芳香环可作为药物设计的模板,并且可以通过在微波条件下对适当取代的炔烃进行热解来方便地制备。