Seitz Marc A, Burkitt-Creedon Jamie M
Emergency Department, Red Bank Veterinary Hospital - Cherry Hill, Cherry Hill, NJ, 08108.
J Vet Emerg Crit Care (San Antonio). 2016 Nov;26(6):804-808. doi: 10.1111/vec.12440. Epub 2016 Jan 8.
To describe the observation of persistent gross lipemia and suspected corneal lipidosis following intravenous lipid therapy (IVLT) in a cat with permethrin toxicosis.
A 5-year-old, spayed female, domestic short-haired cat with permethrin toxicosis was treated with a high dose of IVLT as an adjunct treatment when it remained severely obtunded following traditional supportive care. The cat received intravenous 20% lipid emulsion as a 1.5 mL/kg bolus given over 10 minutes followed by a constant rate infusion of 0.25 mL/kg/min for 2 hours. The cat developed gross lipemia that persisted at least 48 hours after the single dose of IVLT. Changes consistent with corneal lipidosis were observed and resolved within 1 week after IVLT.
This is the first report documenting the complications of persistent gross lipemia and suspected corneal lipidosis in a cat following IVLT. This report underscores the off-label, experimental nature of IVLT as a treatment for intoxication in cats.
描述一只患有氯菊酯中毒的猫在接受静脉脂质治疗(IVLT)后出现持续性明显脂血症和疑似角膜脂质沉着症的观察情况。
一只5岁已绝育的雌性家养短毛猫患有氯菊酯中毒,在接受传统支持性护理后仍严重昏迷,遂接受高剂量IVLT作为辅助治疗。这只猫静脉注射20%脂质乳剂,以1.5 mL/kg的剂量在10分钟内推注,随后以0.25 mL/kg/分钟的速率持续输注2小时。这只猫出现了明显的脂血症,在单次IVLT后至少持续了48小时。观察到与角膜脂质沉着症相符的变化,并在IVLT后1周内消退。
这是第一份记录猫在IVLT后出现持续性明显脂血症和疑似角膜脂质沉着症并发症的报告。本报告强调了IVLT作为猫中毒治疗方法的标签外、实验性质。