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一只患有氯菊酯中毒的猫在接受静脉脂质治疗后出现持续性严重脂血症和疑似角膜脂质沉积症。

Persistent gross lipemia and suspected corneal lipidosis following intravenous lipid therapy in a cat with permethrin toxicosis.

作者信息

Seitz Marc A, Burkitt-Creedon Jamie M

机构信息

Emergency Department, Red Bank Veterinary Hospital - Cherry Hill, Cherry Hill, NJ, 08108.

出版信息

J Vet Emerg Crit Care (San Antonio). 2016 Nov;26(6):804-808. doi: 10.1111/vec.12440. Epub 2016 Jan 8.

DOI:10.1111/vec.12440
PMID:26748969
Abstract

OBJECTIVE

To describe the observation of persistent gross lipemia and suspected corneal lipidosis following intravenous lipid therapy (IVLT) in a cat with permethrin toxicosis.

CASE SUMMARY

A 5-year-old, spayed female, domestic short-haired cat with permethrin toxicosis was treated with a high dose of IVLT as an adjunct treatment when it remained severely obtunded following traditional supportive care. The cat received intravenous 20% lipid emulsion as a 1.5 mL/kg bolus given over 10 minutes followed by a constant rate infusion of 0.25 mL/kg/min for 2 hours. The cat developed gross lipemia that persisted at least 48 hours after the single dose of IVLT. Changes consistent with corneal lipidosis were observed and resolved within 1 week after IVLT.

NEW OR UNIQUE INFORMATION PROVIDED

This is the first report documenting the complications of persistent gross lipemia and suspected corneal lipidosis in a cat following IVLT. This report underscores the off-label, experimental nature of IVLT as a treatment for intoxication in cats.

摘要

目的

描述一只患有氯菊酯中毒的猫在接受静脉脂质治疗(IVLT)后出现持续性明显脂血症和疑似角膜脂质沉着症的观察情况。

病例摘要

一只5岁已绝育的雌性家养短毛猫患有氯菊酯中毒,在接受传统支持性护理后仍严重昏迷,遂接受高剂量IVLT作为辅助治疗。这只猫静脉注射20%脂质乳剂,以1.5 mL/kg的剂量在10分钟内推注,随后以0.25 mL/kg/分钟的速率持续输注2小时。这只猫出现了明显的脂血症,在单次IVLT后至少持续了48小时。观察到与角膜脂质沉着症相符的变化,并在IVLT后1周内消退。

提供的新的或独特信息

这是第一份记录猫在IVLT后出现持续性明显脂血症和疑似角膜脂质沉着症并发症的报告。本报告强调了IVLT作为猫中毒治疗方法的标签外、实验性质。

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Persistent gross lipemia and suspected corneal lipidosis following intravenous lipid therapy in a cat with permethrin toxicosis.一只患有氯菊酯中毒的猫在接受静脉脂质治疗后出现持续性严重脂血症和疑似角膜脂质沉积症。
J Vet Emerg Crit Care (San Antonio). 2016 Nov;26(6):804-808. doi: 10.1111/vec.12440. Epub 2016 Jan 8.
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