Wang Caihui, Su Wen, Su Xingli, Ni Guojun, Liu Tao, Kong Yi
Nat Prod Commun. 2015 Nov;10(11):1989-91.
The gastric mucosa protection effect of three natural plant extracts, Hericium erinaceus (HE), Centella asiatica (CA) and Amomum villosum (AV), were evaluated using the indomethacin damage model. Compared with a single extract, a combination of HE/CA/AV, especially with the ratios of 80:10:10, 45:45:10 and 45:10:45, showed significant synergistic effects for protection of the gastric mucosa with gastric ulcer inhibition rates of 97.8 ± 0.7%, 86.5 ± 2.8% and 86.1 ± 3.6%, respectively. Microscopic appearances of the gastric mucosa were carried out to help confirm the results.
采用吲哚美辛损伤模型评估了三种天然植物提取物，即猴头菇（HE）、积雪草（CA）和砂仁（AV）的胃黏膜保护作用。与单一提取物相比，HE/CA/AV组合，尤其是比例为80:10:10、45:45:10和45:10:45时，对胃黏膜保护显示出显著的协同作用，胃溃疡抑制率分别为97.8±0.7%、86.5±2.8%和86.1±3.6%。进行了胃黏膜的微观观察以辅助确认结果。
