Gifford F
Theor Med. 1989 Jun;10(2):107-22. doi: 10.1007/BF00539877.
This paper examines some criticisms that have been made of two standard genetic methodologies: heritability and path analysis. I conclude that the criticisms should be taken seriously, concerning both the accuracy of heritability measures and their significance. In light of the fact that such studies remain prominent in the literature, I consider what possible rationale they can retain consistent with these criticisms. In particular, I consider (1) a role in the identification of high-risk individuals and (2) a heuristic role in the planning of research strategy.
本文审视了针对两种标准遗传方法学——遗传力和路径分析——所提出的一些批评。我得出结论，这些批评应当被认真对待，涉及遗传力测量的准确性及其意义。鉴于此类研究在文献中仍然占据显著地位，我思考它们能与这些批评保持一致的可能依据。具体而言，我考虑了（1）在识别高风险个体方面的作用，以及（2）在研究策略规划方面的启发式作用。
