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影响疑似急性冠状动脉综合征患者时间依赖性质量指标的因素

Factors Influencing Time-Dependent Quality Indicators for Patients With Suspected Acute Coronary Syndrome.

作者信息

France Daniel J, Levin Scott, Ding Ru, Hemphill Robin, Han Jin, Russ Stephan, Aronsky Dominik, Weinger Matt

机构信息

From the Department of Anesthesiology, Vanderbilt Medical Center, Nashville, Tennessee.

Emergency Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.

出版信息

J Patient Saf. 2020 Mar;16(1):e1-e10. doi: 10.1097/PTS.0000000000000242.

Abstract

OBJECTIVES

Rapid risk stratification and timely treatment are critical to favorable outcomes for patients with acute coronary syndrome (ACS). Our objective was to identify patient and system factors that influence time-dependent quality indicators (QIs) for patients with unstable angina/non-ST elevation myocardial infarction (NSTEMI) in the emergency department (ED).

METHODS

A retrospective, cohort study was conducted during a 42-month period of all patients 24 years or older suspected of having ACS as defined by receiving an electrocardiogram and at least 1 cardiac biomarker test. Cox regression was used to model the effects of patient characteristics, ancillary service use, staffing provisions, equipment availability, and ED and hospital crowding on ACS QIs.

RESULTS

Emergency department adherence rates to national standards for electrocardiogram readout time and biomarker turnaround time were 42% and 37%, respectively. Cox regression models revealed that chief complaints without chest pain and the timing of stress testing and medication administration were associated with the most significant delays.

CONCLUSIONS

Patient and system factors both significantly influenced QI times in this cohort with unstable angina/NSTEMI. These results illustrate both the complexity of diagnosing patients with NSTEMI and the competing effects of clinical and system factors on patient flow through the ED.

摘要

目的

快速风险分层和及时治疗对于急性冠状动脉综合征(ACS)患者获得良好预后至关重要。我们的目的是确定影响急诊科(ED)中不稳定型心绞痛/非ST段抬高型心肌梗死(NSTEMI)患者时间依赖性质量指标(QIs)的患者和系统因素。

方法

进行了一项回顾性队列研究,研究对象为在42个月期间所有年龄在24岁及以上、因接受心电图检查和至少一项心脏生物标志物检测而疑似患有ACS的患者。Cox回归用于模拟患者特征、辅助服务使用、人员配备、设备可用性以及ED和医院拥挤程度对ACS质量指标的影响。

结果

急诊科对心电图读数时间和生物标志物周转时间国家标准的遵守率分别为42%和37%。Cox回归模型显示,无胸痛的主要症状以及负荷试验和药物给药的时间与最显著的延迟相关。

结论

患者和系统因素均对该不稳定型心绞痛/NSTEMI队列中的质量指标时间产生显著影响。这些结果说明了诊断NSTEMI患者的复杂性以及临床和系统因素对患者通过ED的流程的相互竞争影响。

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