Iakovlev M Iu, Kubatiev A A, Krupnik A N, Bondarenko V M, Sudzhan E V
Biull Eksp Biol Med. 1989 Jun;107(6):765-6.
With the help of immunofluorescent diagnostic system (specific immunoglobulins against glycolipid of S. minnesota Re-595) has been shown to permit the detection of endotoxin into eosinophil. Statistically significant differences in the occurrence of endotoxin in eosinophils of patients and healthy persons have been revealed. These data allow us to suppose that eosinophils are superaffined endotoxin-interaction cells of the human blood. Eosinopenia may be taken into account as an indirect marker of systemic LPS O-antigen mediated endotoxinemia.
借助免疫荧光诊断系统(针对明尼苏达沙门氏菌Re-595糖脂的特异性免疫球蛋白)已表明可检测嗜酸性粒细胞中的内毒素。已揭示患者和健康人嗜酸性粒细胞中内毒素出现情况的统计学显著差异。这些数据使我们推测嗜酸性粒细胞是人体血液中与内毒素相互作用的超亲和细胞。嗜酸性粒细胞减少可被视为全身性脂多糖O抗原介导的内毒素血症的间接标志物。