Pereira Rita Calado, Barroso Laura Martins, Mendes Maria José, Joaquim Isabel Fernandes, Ornelas Helder
Hospital do Espírito Santo, Evora, PT.
Einstein (Sao Paulo). 2011 Mar;9(1):78-80. doi: 10.1590/S1679-45082011RC1891.
Congenital goiter is a rare cause of neonatal neck mass and may result from a fetal defectin synthesis of thyroxine, or administration of antithyroid drugs or iodides during pregnancy. The thyroid dysfunction often accompanies it. This report describes a case of a male term newborn with congenital goiter and primary hypothyroidism. Hormonal replacement treatment was started leading to normal levels of free thyroxine and triiodothyronine. In face of a maternal negative investigation, dyshormonogenesis was considered to be the most probable cause of hypothyroidism.
先天性甲状腺肿是新生儿颈部肿块的罕见病因，可能源于胎儿甲状腺素合成缺陷，或孕期服用抗甲状腺药物或碘化物。甲状腺功能障碍常与之相伴。本报告描述了一例足月男婴先天性甲状腺肿并原发性甲状腺功能减退的病例。开始进行激素替代治疗，使游离甲状腺素和三碘甲状腺原氨酸水平恢复正常。鉴于母亲检查结果为阴性，甲状腺激素合成障碍被认为是甲状腺功能减退最可能的原因。
