Department of Chemistry (Centre of Advanced Study), Faculty of Science, Banaras Hindu University, Varanasi-, 221005, India.
Chem Asian J. 2016 Mar 4;11(5):696-9. doi: 10.1002/asia.201501385. Epub 2016 Jan 28.
A novel and site selective C-H functionalization of unsubstituted sulfonamides has been developed for the synthesis of ortho aryl sulfonamides. The reaction involves highly regioselective ortho mono arylation of weakly coordinating SO2 NH2 directing group by means of aryl iodides. Palladium acetate in the presence of silver(I) oxide is found to be the most effective catalytic system.
发展了一种新颖的、位点选择性的未取代磺酰胺的 C-H 官能化方法，用于合成邻位芳基磺酰胺。该反应涉及通过芳基碘化物实现弱配位 SO2 NH2 导向基团的高区域选择性邻位单芳基化。发现醋酸钯在氧化银存在下是最有效的催化体系。
