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中国人群中睡眠时间与高血压发病之间的年龄和性别特异性关联:开滦研究

Age- and gender-specific associations between sleep duration and incident hypertension in a Chinese population: the Kailuan study.

作者信息

Song Q, Liu X, Wang X, Wu S

机构信息

Department of Cardiology, Tangshan People's Hospital, North China University of Science and Technology, Tangshan, China.

Department of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China.

出版信息

J Hum Hypertens. 2016 Aug;30(8):503-7. doi: 10.1038/jhh.2015.118. Epub 2016 Jan 14.

Abstract

The objective of this study was to explore the age- and sex-dependent association between sleep duration and incident hypertension in a Chinese population. The Kailuan prospective cohort study recruited 101 510 participants. Those participants were followed for an average of 3.98 years and the data obtained from 32 137 participants out of 101 510 were analyzed in this study. Sleep duration was categorized as five groups of⩽5, 6, 7, 8 and ⩾9 h. Cox proportional-hazards models were used to analyze the association of sleep duration with incident hypertension. The 3.98 years' follow-up data showed that 12 732 out of 32 137 participants developed hypertension. Short duration of sleep (⩽5 h per night) was associated with an increased risk of hypertension in woman (hazard ratio (HR) 1.27; 95% confidence interval (CI) 1.02 to 1.58) and participants aged <60 years (HR 1.11; 95% CI 1.02-1.21), when compared with the group reported with 7 h of sleep per day. This study suggested that short sleep duration could cause an increased risk of hypertension in Chinese females and population aged <60 years.

摘要

本研究的目的是探讨中国人群中睡眠时间与高血压发病之间的年龄和性别依赖性关联。开滦前瞻性队列研究招募了101510名参与者。这些参与者平均随访3.98年,本研究分析了101510名参与者中32137名参与者的数据。睡眠时间分为五组:≤5小时、6小时、7小时、8小时和≥9小时。采用Cox比例风险模型分析睡眠时间与高血压发病的关联。3.98年的随访数据显示,32137名参与者中有12732人患高血压。与报告每天睡眠7小时的组相比,睡眠时间短(每晚≤5小时)与女性高血压风险增加相关(风险比(HR)1.27;95%置信区间(CI)1.02至1.58),以及与年龄<60岁的参与者(HR 1.11;95%CI 1.02-1.21)相关。本研究表明,睡眠时间短可能会增加中国女性和<60岁人群患高血压的风险。

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