Katsnelson B A, Polzik E V, Morosova K I, Privalova L I, Kislitsina N S, Kasantsev V S
Laboratory of Experimental Pneumoconioses, Institute of Industrial Hygiene, Sverdlovsk, USSR.
Environ Health Perspect. 1989 Jul;82:311-21. doi: 10.1289/ehp.82-1568111.
Based on earlier paper in this journal, as well as on new data concerning factors predetermining individual susceptibility to silicosis, we propose a comprehensive system of recommendations aimed at increasing the working population's resistance against the harmful action of silica dust. These recommendations consider, on one hand, the criteria of possible selection for employment in dusty industries of individuals who do not possess characteristics making them especially sensitive to this harmful action (collective biological prophylaxis), and on the other hand, the influences that could diminish such sensitivity (individual biological prophylaxis). Some ethical and practical problems of the biological prophylaxis of occupational diseases and a mathematical approach to predicting its effectiveness are also discussed.
基于本期刊早期发表的论文以及有关决定个体对矽肺病易感性的因素的新数据，我们提出了一套全面的建议体系，旨在增强劳动人口对二氧化硅粉尘有害作用的抵抗力。这些建议一方面考虑了在粉尘行业就业时，对那些不具备使其对这种有害作用特别敏感特征的个体进行可能的筛选标准（集体生物预防），另一方面考虑了可能降低这种敏感性的影响因素（个体生物预防）。还讨论了职业病生物预防的一些伦理和实际问题以及预测其有效性的数学方法。
