Finkelstein M M
Health and Safety Studies Unit, Ontario Ministry of Labour, Toronto, Canada.
Scand J Work Environ Health. 1995;21 Suppl 2:55-7.
This paper reports the detection rates of silicosis among silica-exposed persons first exposed to dust in 1950 or later and still employed in 1979 or later in the province of Ontario. The rate varied strongly with latency, being less than two new cases per 10 000 examinations during the first two decades from first exposure, reaching two new cases per 1000 examinations at 27 years from first exposure, and averaging between two and four new cases per 1000 examinations thereafter. A Poisson regression analysis found that the silicosis rate in the interval after 30 years from first exposure was more than 16 times higher than the rate prior to 20 years from first exposure. There was no significant difference in the diagnosis rates among the workers in the mining, primary metal, and nonmetallic mineral industries sectors. The rate of silicosis was higher among smokers than among never smokers (rate ratio 1.54).
本文报告了安大略省1950年或之后首次接触粉尘且在1979年或之后仍受雇的接触二氧化硅人员中的矽肺病检出率。该比率随潜伏期变化很大，首次接触后的头二十年中每10000次检查中新增病例少于2例，首次接触27年后每1000次检查中新增病例达2例，此后每1000次检查中新增病例平均在2至4例之间。泊松回归分析发现，首次接触30年后的矽肺病发病率比首次接触20年前的发病率高出16倍多。采矿、初级金属和非金属矿物行业部门的工人诊断率没有显著差异。吸烟者的矽肺病发病率高于从不吸烟者（发病率比为1.54）。
