Chen Feng, Liu Yu-hua, Yang Hui, Duan Yii-chun, Yang Jing, Zhao Yin-jiao, Hao Ming-ming, Pan Li-juan, Deng Yin-ju, Shi Ya-nan, Chen Fu-ling, Zhang Jian-guo, Luo Jia-jun
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2015 Aug;27(4):399-402.
To understand the infection status of Fasciola and related risk factors in population of Binchuan County, Yunnan Province.
In February and March, 2014, 6 natural villages from 2 administrative villages in Zhoucheng Town were selected as investigated sites, and the permanent residents aged ≥ 5 years were examined by ELISA for the serum antibody detection, and then the positive ones were examined by Kato-Katz technique and the hatching method for Fasciola egg detection. Meanwhile, the fascioliasis cases that checked out by the above methods were further surveyed, and the residents who with the same gender, similar age and negative results in the blood examination were selected as the controls, then the risk factors were explored through a case control study.
Totally 1 207 people were included in the blood examination, and 36 positives were found with a positive rate of 2.98%. Though the differences between the positive rates of the serum antibody in people with different genders and age were not statistically significant (χ2 = 1.686, 7.106, both P > 0.05) , those between the rates of people in different administrative villages and natural villages were statistically significant (χ2 = 4.103, 13.181, both P < 0.05). Two cases were determined as positives in fecal examinations with a positive rate of 6.45% (2/31), among which, 1 case was newly discovered. The case control study showed that OR values of eating out- purchased cold dish (4.30), raw mint (1.22) , raw leek (4.30) and drinking unboiled-water (3.75) were relatively higher, but all of them were not statistically significant (χ2 = 0.524, 0.046, 0.524, 1.571, all P > 0.05).
There is still sporadic Fasciola infection in Binchuan County. Eating raw vegetables and drinking unboiled water which are contaminated by Fasciola metacercariae may be the infection routes of local people, and to find out the exact entrance way is the key points for the infection control.
了解云南省宾川县人群肝片吸虫感染状况及相关危险因素。
2014年2月和3月，选取周城镇2个行政村的6个自然村作为调查点，对年龄≥5岁的常住人口采用酶联免疫吸附试验（ELISA）进行血清抗体检测，阳性者再采用加藤厚涂片法和虫卵孵化法进行肝片吸虫虫卵检测。同时，对上述方法检出的肝片吸虫病病例进行进一步调查，选取性别、年龄相近且血液检查结果为阴性的居民作为对照，通过病例对照研究探索危险因素。
共纳入血液检查1 207人，阳性36人，阳性率为2.98%。不同性别和年龄人群血清抗体阳性率差异无统计学意义（χ2 = 1.686, 7.106，均P > 0.05），但不同行政村和自然村人群阳性率差异有统计学意义（χ2 = 4.103, 13.181，均P < 0.05）。粪便检查确定阳性2例，阳性率为6.45%（2/31），其中新发现1例。病例对照研究显示，外出就餐购买凉拌菜（比值比[OR]=4.30）、生食薄荷（OR = 1.22）、生食韭菜（OR = 4.30）和饮用生水（OR = 3.75）的OR值相对较高，但均无统计学意义（χ2 = 0.524, 0.046, 0.524, 1.571，均P > 0.05）。
宾川县仍存在肝片吸虫散在感染。生食被肝片吸虫囊蚴污染的蔬菜和饮用生水可能是当地人群的感染途径，明确具体感染途径是控制感染的关键。
