Wang Zhan-yi, Zhang Li-hua, Wang Yu-hai, Zhang Yuan-hu, Ma Li, Zheng Dan-dan
Zhong Yao Cai. 2015 May;38(5):1060-5.
The dynamic mathematical model of ultrasonic extraction of polyphenols from pomegranate peel was constructed with the Fick's second law as the theoretical basis.
The spherical model was selected, with mass concentrations of pomegranate peel polyphenols as the index, 50% ethanol as the extraction solvent and ultrasonic extraction as the extraction method. In different test conditions including the liquid ratio, extraction temperature and extraction time, a series of kinetic parameters were solved, such as the extraction process (k), relative raffinate rate, surface diffusion coefficient(D(S)), half life (t½) and the apparent activation energy (E(a)).
With the extraction temperature increasing, k and D(S) were gradually increased with t½ decreasing,which indicated that the elevated temperature was favorable to the extraction of pomegranate peel polyphenols. The exponential equation of relative raffinate rate showed that the established numerical dynamics model fitted the extraction of pomegranate peel polyphenols, and the relationship between the reaction conditions and pomegranate peel polyphenols concentration was well reflected by the model.
Based on the experimental results, a feasible and reliable kinetic model for ultrasonic extraction of polyphenols from pomegranate peel is established, which can be used for the optimization control of engineering magnifying production.
以菲克第二定律为理论基础，构建石榴皮多酚超声提取的动态数学模型。
选用球形模型，以石榴皮多酚质量浓度为指标，50%乙醇为提取溶剂，超声提取为提取方法。在不同的试验条件下，包括液比、提取温度和提取时间，求解了一系列动力学参数，如提取过程（k）、相对萃余率、表面扩散系数（D(S)）、半衰期（t½）和表观活化能（E(a)）。
随着提取温度升高，k和D(S)逐渐增大，t½减小，表明升高温度有利于石榴皮多酚的提取。相对萃余率的指数方程表明所建立的数值动力学模型拟合了石榴皮多酚的提取，该模型很好地反映了反应条件与石榴皮多酚浓度之间的关系。
基于实验结果，建立了一种可行、可靠的石榴皮多酚超声提取动力学模型，可用于工程放大生产的优化控制。
