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用于复杂未破裂动脉瘤血管内治疗的编织型血管内桥接(WEB)装置——单中心经验

Woven Endobridge (WEB) device for endovascular treatment of complex unruptured aneurysms-a single center experience.

作者信息

Lescher Stephanie, du Mesnil de Rochemont Richard, Berkefeld Joachim

机构信息

Institute of Neuroradiology, Hospital of Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.

出版信息

Neuroradiology. 2016 Apr;58(4):383-90. doi: 10.1007/s00234-016-1641-x. Epub 2016 Jan 15.

Abstract

INTRODUCTION

The introduction of the Woven Endobridge (WEB) device increases the feasibility of endovascular treatment of wide-neck bifurcation aneurysms with limitations given by currently available sizes and shapes of the device. Parallel to other studies, we used the new device for selected patients who were no optimal candidates for established techniques like neurosurgical clipping or endovascular coiling. We aimed to report the angiographic and clinical results of WEB implantations or combinations between WEB and coiling or intracranial stents.

METHODS

We reviewed the records of n = 23 interventions in 22 patients with unruptured wide-neck aneurysms (UIA) who were assigned for aneurysm treatment with the use of the WEB or adjunctive techniques. Interventional procedures and clinical and angiographic outcomes are reported for the periprocedural phase and in mid-term FU.

RESULTS

Of the included 22 patients, six patients needed additional coiling, intracranial stenting, or implantation of a flow diverter. WEB implantation was technically feasible in 22 out of the 23 interventions. Follow-up angiographic imaging proved total or subtotal occlusion of the aneurysm in 19 of 22 cases. Two minor recurrences remained stable during a period of 15 months. One patient with a partially thrombosed giant MCA aneurysm had a major recurrence and was retreated with a second WEB in combination with coiling.

CONCLUSION

Despite of unfavorable anatomic conditions, broad-based and large UIA endovascular treatment with the WEB and adjunctive techniques was feasible with a low risk of complications and promising occlusion rates in mid-term follow-up.

摘要

引言

编织型血管内桥接器(WEB)的引入增加了血管内治疗宽颈分叉动脉瘤的可行性,但该装置目前的尺寸和形状存在一定限制。与其他研究类似,我们将这种新装置用于那些不适合采用神经外科夹闭或血管内栓塞等现有技术的特定患者。我们旨在报告WEB植入术以及WEB与栓塞或颅内支架联合使用的血管造影和临床结果。

方法

我们回顾了22例未破裂宽颈动脉瘤(UIA)患者的23次干预记录,这些患者被指定采用WEB或辅助技术进行动脉瘤治疗。报告了围手术期和中期随访期间的介入操作以及临床和血管造影结果。

结果

在纳入的22例患者中,6例患者需要额外的栓塞、颅内支架置入或血流导向装置植入。在23次干预中,22次WEB植入在技术上是可行的。随访血管造影显示,22例中有19例动脉瘤完全或接近完全闭塞。2例轻微复发在15个月内保持稳定。1例患有部分血栓形成的大脑中动脉巨大动脉瘤患者出现了主要复发,并再次接受了第二次WEB联合栓塞治疗。

结论

尽管解剖条件不利,但采用WEB及辅助技术对基底较宽的大型UIA进行血管内治疗是可行的,并发症风险低,中期随访时的闭塞率前景良好。

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