Kalita Jayantee, Uniyal Ravi, Bhoi Sanjeev K
Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Cephalalgia. 2016 Nov;36(13):1248-1256. doi: 10.1177/0333102415625610. Epub 2016 Jul 11.
Background We report the occurrence of palinopsia in patients with migraine and its correlation with migraine characteristics, triggers and allodynia. Methods This study included 153 consecutive patients with migraine and recorded their clinical details, including allodynia and migraine triggers and characteristics. Palinopsia was evaluated in migraineurs and 101 controls by using a questionnaire and a novel method. Results According to the questionnaire assessment, 9.8% migraineurs had palinopsia. According to the novel method, 57.5% of migraineurs and 12% of controls had palinopsia. Migraineurs most frequently had palinopsia to red color (51.6%), followed by yellow (49.7%), blue (47.7%), green (46.4%) and the least to white (30.7%). A similar pattern with a lesser frequency was noted in controls. The duration of palinopsia was longer in migraineurs than in controls (32.68 ± 20.24 vs. 5.92 ± 4.55 seconds; p < 0.001). Migraineurs with palinopsia differed from those without in terms of noise as a migraine trigger ( p < 0.001) and allodynia as a migraine-associated phenomenon ( p = 0.03). In multivariable analysis, predictors of palinopsia were the frequency ( p = 0.003) and severity ( p = 0.04) of headache and the presence of headache during examination ( p = 0.0001). Conclusion Migraineurs had a pattern of palinopsia to different colors that was similar to the controls, but the palinopsia of migraineurs was more frequent and of longer duration, especially during headaches.
背景 我们报告偏头痛患者中持续性视幻觉的发生情况及其与偏头痛特征、诱发因素和痛觉过敏的相关性。方法 本研究纳入153例连续性偏头痛患者，并记录其临床细节，包括痛觉过敏、偏头痛诱发因素和特征。通过问卷调查和一种新方法对偏头痛患者和101名对照者进行持续性视幻觉评估。结果 根据问卷调查评估，9.8%的偏头痛患者有持续性视幻觉。根据新方法，57.5%的偏头痛患者和12%的对照者有持续性视幻觉。偏头痛患者持续性视幻觉最常出现于红色（51.6%），其次是黄色（49.7%）、蓝色（47.7%）、绿色（46.4%），最少出现于白色（30.7%）。对照者中也观察到类似模式，但频率较低。偏头痛患者持续性视幻觉的持续时间比对照者长（32.68±20.24秒 vs. 5.92±4.55秒；p<0.001）。有持续性视幻觉的偏头痛患者与无持续性视幻觉的患者在作为偏头痛诱发因素的噪音方面（p<0.001）以及作为偏头痛相关现象的痛觉过敏方面（p=0.03）存在差异。在多变量分析中，持续性视幻觉的预测因素为头痛频率（p=0.003）、严重程度（p=0.04）以及检查时头痛的存在情况（p=0.0001）。结论 偏头痛患者对不同颜色的持续性视幻觉模式与对照者相似，但偏头痛患者的持续性视幻觉更频繁且持续时间更长，尤其是在头痛期间。
