Albers Brittany K, Sluzevich Jason C, Garner Hillary W
Department of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Department of Dermatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Skeletal Radiol. 2016 May;45(5):717-21. doi: 10.1007/s00256-015-2326-y. Epub 2016 Jan 15.
Sarcoidosis is a granulomatous disease which can affect multiple organ systems. Clinical and radiologic manifestations depend on the organ system involved and the chronicity of disease. Nail involvement in sarcoidosis is rare, but is clinically relevant as it indicates chronic systemic disease. Nail abnormalities can be identified radiographically, and when seen in patients with known or suspected sarcoidosis, should prompt careful evaluation of the underlying bone for osseous involvement. We describe a case of sarcoidosis with radiographic findings in the nails and distal phalangeal tufts, which were indicative of nail and osseous sarcoid involvement and strongly supported the presence of chronic systemic disease. Although the nail findings resolved clinically and on radiographs after treatment, the osseous findings showed only minimal improvement. To our knowledge, the radiographic findings of nail sarcoidosis have not been previously addressed in the literature.
结节病是一种可累及多个器官系统的肉芽肿性疾病。其临床和影像学表现取决于受累的器官系统及疾病的慢性程度。结节病累及指甲较为罕见，但具有临床相关性，因为这表明存在慢性全身性疾病。指甲异常可通过影像学检查发现，当在已知或疑似结节病的患者中出现时，应促使对潜在骨骼进行仔细评估以确定是否存在骨质受累。我们描述了一例结节病患者，其指甲和远端指骨簇有影像学表现，提示指甲和骨质存在结节病累及，有力地支持了慢性全身性疾病的存在。尽管治疗后指甲表现临床和影像学上均有所缓解，但骨质表现仅略有改善。据我们所知，指甲结节病的影像学表现此前在文献中尚未有过论述。
