Ahuja Nitin K, Chan Walter W
Division of Gastroenterology and Hepatology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.
Curr Gastroenterol Rep. 2016 Feb;18(2):7. doi: 10.1007/s11894-015-0480-y.
The upper esophageal sphincter constitutes an important anatomic and functional landmark in the physiology of pharyngeal swallowing. A variety of clinical circumstances may call for a dedicated evaluation of this mechanism, from the etiologic evaluation of indeterminate symptoms to the generation of complex locoregional therapeutic strategies. Multiple diagnostic tools exist for the assessment of pharyngeal swallowing generally and of upper esophageal sphincter function specifically, some well established and others not yet settled into routine practice. This report reviews five specific modalities for use in making this assessment, outlining the strengths, weaknesses, and logistical considerations of each with respect to its potential use in clinical settings. In many cases, these studies will provide complementary information regarding pharyngeal function, suggesting the relative advantage of a multimodal evaluation.
上食管括约肌是咽吞咽生理学中一个重要的解剖学和功能标志。从对不明症状进行病因评估到制定复杂的局部区域治疗策略，多种临床情况可能需要对该机制进行专门评估。一般来说，有多种诊断工具可用于评估咽吞咽，特别是评估上食管括约肌功能，其中一些已得到广泛认可，而另一些尚未纳入常规实践。本报告回顾了用于进行该评估的五种具体方法，概述了每种方法在临床应用中的优势、劣势及后勤方面的考虑因素。在许多情况下，这些研究将提供有关咽功能的补充信息，提示多模式评估的相对优势。
