Atigari Onome V, Harris Margaret, Le Noury Joanna, Healy David
North Wales Department of Psychological Medicine, Hergest Unit, Bangor, Wales.
North Wales Department of Psychological Medicine, Hergest Unit, Bangor, Wales
Hist Psychiatry. 2016 Mar;27(1):75-84. doi: 10.1177/0957154X15624601. Epub 2016 Jan 14.
We compared admission rates and outcomes for bipolar disorder patients using the medical records of patients with a first hospital admission in 1875-1924 retrospectively diagnosed based on International Classification of Diseases (ICD)-10 criteria, and patients with a first admission in 1994-2007. The incidences of first admissions in the historical and contemporary periods are comparable: 1.2 and 1.3 per hundred thousand per year, respectively. Manic episodes constituted a greater proportion of admissions historically, while depressive episodes made up more in the contemporary sample. There is no evidence for a reduction in the mean inter-admission intervals with duration of illness. This study suggests that modern treatments may have decreased lengths of stay in hospital, but at a cost of contributing to more admissions. It also points to a shift in the threshold for admissions.
我们利用1875 - 1924年首次住院患者的病历，根据国际疾病分类（ICD）-10标准进行回顾性诊断，与1994 - 2007年首次住院的双相情感障碍患者比较入院率和治疗结果。历史时期和当代时期首次入院的发生率相近：分别为每年十万分之1.2和1.3。历史上躁狂发作构成入院的比例更大，而在当代样本中抑郁发作占比更多。没有证据表明随着患病时间推移，平均两次入院间隔时间缩短。本研究表明，现代治疗可能缩短了住院时间，但代价是导致更多的入院情况。它还指出了入院阈值的变化。
