Concurrent whole brain radiotherapy and RRx-001 for melanoma brain metastases.
作者信息
Kim Michelle M, Parmar Hemant, Cao Yue, Knox Susan J, Oronsky Bryan, Scicinski Jan, Lawrence Theodore S, Lao Christopher D
机构信息
University of Michigan, Ann Arbor, Michigan (M.M.K., H.P., Y.C., T.S.L., C.D.L.); Stanford University School of Medicine, Radiation Oncology, Stanford, California (S.J.K.); EpicentRx, Inc, Mountain View, California (B.O., J.S.).
出版信息
Neuro Oncol. 2016 Mar;18(3):455-6. doi: 10.1093/neuonc/nov317. Epub 2016 Jan 13.
Abstract
摘要
相似文献
1
Concurrent whole brain radiotherapy and RRx-001 for melanoma brain metastases.同步全脑放疗联合RRx-001治疗黑色素瘤脑转移瘤。
Neuro Oncol. 2016 Mar;18(3):455-6. doi: 10.1093/neuonc/nov317. Epub 2016 Jan 13.
2
BRAINSTORM: A Multi-Institutional Phase 1/2 Study of RRx-001 in Combination With Whole Brain Radiation Therapy for Patients With Brain Metastases.BRCAINSTORM：一项多机构 1/2 期研究，评估 RRx-001 联合全脑放疗治疗脑转移瘤患者的疗效。
Int J Radiat Oncol Biol Phys. 2020 Jul 1;107(3):478-486. doi: 10.1016/j.ijrobp.2020.02.639. Epub 2020 Mar 10.
3
Disease presentation and outcome in young patients (<40 years) with brain metastases from malignant melanoma.
Anticancer Res. 2008 Mar-Apr;28(2B):1325-7.
4
Whole-brain radiation therapy in melanoma: an open question.黑色素瘤的全脑放射治疗：一个悬而未决的问题。
Lancet Oncol. 2010 Jan;11(1):13; author reply 13-4. doi: 10.1016/S1470-2045(09)70346-8.
5
A Complete Metabolic Response of Metastatic Castration-resistant Neuroendocrine Carcinoma of the Prostate After Treatment with RRx-001 and Reintroduced Platinum Doublets.RRx-001及重新引入的铂类双联疗法治疗后转移性去势抵抗性前列腺神经内分泌癌的完全代谢反应
Eur Urol. 2018 Feb;73(2):306-307. doi: 10.1016/j.eururo.2017.09.010. Epub 2017 Sep 21.
6
7
Potential role for LINAC-based stereotactic radiosurgery for the treatment of 5 or more radioresistant melanoma brain metastases.基于直线加速器的立体定向放射外科治疗5个或更多放射性抵抗性黑色素瘤脑转移瘤的潜在作用。
J Neurosurg. 2015 Nov;123(5):1261-7. doi: 10.3171/2014.12.JNS141919. Epub 2015 Jul 3.
8
Dose escalation of whole-brain radiotherapy for brain metastases from melanoma.脑转移瘤的全脑放疗剂量递增。
Int J Radiat Oncol Biol Phys. 2010 Jun 1;77(2):537-41. doi: 10.1016/j.ijrobp.2009.05.001. Epub 2009 Sep 3.
9
Rockets, radiosensitizers, and RRx-001: an origin story part I.火箭、放射增敏剂与RRx-001：起源故事第一部
Discov Med. 2016 Mar;21(115):173-80.
10
[CNS metastases in malignant melanomas].[恶性黑色素瘤的中枢神经系统转移]
Strahlenther Onkol. 1995 Mar;171(3):165-73.
引用本文的文献
1
RRx-001 Radioprotection: Enhancement of Survival and Hematopoietic Recovery in Gamma-Irradiated Mice.RRx-001的辐射防护作用：提高γ射线照射小鼠的存活率及促进造血恢复
Front Pharmacol. 2021 Apr 22;12:676396. doi: 10.3389/fphar.2021.676396. eCollection 2021.
2
RRx-001 Increases Erythrocyte Preferential Adhesion to the Tumor Vasculature.RRx-001 增加红细胞对肿瘤血管的优先黏附。
Int J Mol Sci. 2021 Apr 29;22(9):4713. doi: 10.3390/ijms22094713.
3
Results from a biomarker study to accompany a phase II trial of RRx-001 with reintroduced platinum-based chemotherapy in relapsed small cell carcinoma.伴随 RRx-001 联合重新引入铂类化疗二线治疗复发小细胞癌的 II 期试验的生物标志物研究结果。
Expert Opin Investig Drugs. 2021 Feb;30(2):177-183. doi: 10.1080/13543784.2021.1863947. Epub 2021 Jan 11.
4
Magnetic resonance imaging of RRx-001 pharmacodynamics in preclinical tumors.RRx-001在临床前肿瘤中药效学的磁共振成像
Oncotarget. 2017 Jun 12;8(60):102511-102520. doi: 10.18632/oncotarget.18455. eCollection 2017 Nov 24.
5
RRx-001 protects against cisplatin-induced toxicities.RRx-001可预防顺铂诱导的毒性反应。
J Cancer Res Clin Oncol. 2017 Sep;143(9):1671-1677. doi: 10.1007/s00432-017-2416-4. Epub 2017 Apr 17.
6
A Partial Response to Reintroduced Chemotherapy in a Resistant Small Cell Lung Cancer Patient After Priming with RRx-001.RRx-001预处理后，一名耐药小细胞肺癌患者对重新引入的化疗产生部分反应。
Clin Med Insights Oncol. 2016 Nov 6;10:105-108. doi: 10.4137/CMO.S40429. eCollection 2016.
本文引用的文献
1
Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study.RRx-001 治疗晚期癌症患者的安全性和活性：首次人体、开放标签、剂量递增的 1 期研究。
Lancet Oncol. 2015 Sep;16(9):1133-1142. doi: 10.1016/S1470-2045(15)00089-3. Epub 2015 Aug 19.
2
Cerebral melanoma metastases: a critical review on diagnostic methods and therapeutic options.脑黑色素瘤转移：关于诊断方法和治疗选择的批判性综述
ISRN Surg. 2011;2011:276908. doi: 10.5402/2011/276908. Epub 2011 May 25.
3
Prognostic factors for outcomes after whole-brain irradiation of brain metastases from relatively radioresistant tumors: a retrospective analysis.相对放射抗拒肿瘤脑转移全脑放疗后结局的预后因素：回顾性分析。
BMC Cancer. 2010 Oct 26;10:582. doi: 10.1186/1471-2407-10-582.
Zotero 插件