Flanagan Michael F
American Chiropractic Association, 1701 Clarendon Boulevard, Suite 200, Arlington, VA 22209, USA; American Chiropractic Neurology Board, 3710 Robinhood Drive, Temple, TX 76502, USA.
Neurol Res Int. 2015;2015:794829. doi: 10.1155/2015/794829. Epub 2015 Nov 30.
The craniocervical junction (CCJ) is a potential choke point for craniospinal hydrodynamics and may play a causative or contributory role in the pathogenesis and progression of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, MS, and ALS, as well as many other neurological conditions including hydrocephalus, idiopathic intracranial hypertension, migraines, seizures, silent-strokes, affective disorders, schizophrenia, and psychosis. The purpose of this paper is to provide an overview of the critical role of the CCJ in craniospinal hydrodynamics and to stimulate further research that may lead to new approaches for the prevention and treatment of the above neurodegenerative and neurological conditions.
颅颈交界区（CCJ）是颅脊液动力学的一个潜在狭窄点，可能在神经退行性疾病如阿尔茨海默病、帕金森病、多发性硬化症和肌萎缩侧索硬化症以及许多其他神经疾病（包括脑积水、特发性颅内高压、偏头痛、癫痫、无症状性卒中、情感障碍、精神分裂症和精神病）的发病机制和进展中起致病或促成作用。本文的目的是概述颅颈交界区在颅脊液动力学中的关键作用，并激发进一步的研究，这可能会带来预防和治疗上述神经退行性和神经疾病的新方法。
