Oliveira Matheus F, Oliveira João R M, Rotta José M, Pinto Fernando C G
Departamento de Neurocirurgia, Hospital do Servidor Público Estadual de São Paulo, Sao Paulo, SP, Brazil.
Laboratório Keizo Asami, Universidade Federal do Recife, Recife, PE, Brazil.
Arq Neuropsiquiatr. 2014 Jun;72(6):435-8. doi: 10.1590/0004-282x20140047.
Normal pressure hydrocephalus (NPH) is characterized by gait disturbance, dementia and/or urinary incontinence associated with dilation of ventricular system with normal opening cerebrospinal fluid pressure. Wide scientifical evidence confirms association between NPH and psychiatric symptoms. We selected 35 patients with idiopathic normal pressure hydrocephalus from January 2010 to January 2012 in a Brazilian tertiary hospital and performed a formal psychiatric evaluation to identify psychiatric disorders. Psychiatric disorders were present in 71% of these patients, especially anxiety, depression and psychotic syndromes. NPH patients may develop symptoms with frontal dominance, such as personality changes, anxiety, depression, psychotic syndromes, obsessive compulsive disorder, Othello syndrome; shoplifting and mania. Unusual appearances of NPH symptoms may hinder early diagnosis and consequently proper treatment.
正常压力脑积水(NPH)的特征是步态障碍、痴呆和/或尿失禁,伴有脑室系统扩张且脑脊液压力正常。大量科学证据证实了NPH与精神症状之间的关联。我们于2010年1月至2012年1月在巴西一家三级医院选取了35例特发性正常压力脑积水患者,并进行了正式的精神评估以确定精神障碍。这些患者中有71%存在精神障碍,尤其是焦虑、抑郁和精神病综合征。NPH患者可能出现以额叶为主导的症状,如人格改变、焦虑、抑郁、精神病综合征、强迫症、奥赛罗综合征;盗窃癖和躁狂。NPH症状的异常表现可能会妨碍早期诊断,从而影响恰当的治疗。