Girardet M, Jacotot B, Mendy F, Piganeau P, Beaumont J L
J Med. 1977;8(3-4):261-78.
Male Sprague-Dawley rats were fed during one year with diets containing 12% of one of the following fats: butter, sunflower oil, rapeseed oil, soybean oil, hydrogenated soybean oil, palm oil, canbra oil and arachid oil. Total serum cholesterol was lower in the arachid, suflower and butter groups and higher in the palm and hydrogenated soybean groups (p less than 0.01); serum cholesterol esters were lower in the arachid, sunflower and soybean groups, but higher in the palm and hydrogenated soybean groups ( p less than 0.01). Serum triglycerides were lower in the sunflower and arachid groups and higher in the butter and palm groups (p less than 0.01). There was a positive, significant correlation between serum cholesterol and phospholipids in the various groups. In aortas, free cholesterol levels were the same in different groups, but cholesterol ester levels increased in the following order: canbra, butter, arachid, palm, sunflower, rapeseed, hydrogenated soybean and soybean red groups (p less than 0.01). There was a significant correlation between aorta cholesterol esters and the ratio 18:0 + 18:1 of the dietary fat (r = 0.69; p less than 0.001).
将雄性斯普拉格-道利大鼠用含有以下其中一种脂肪(含量为12%)的饲料喂养一年:黄油、葵花籽油、菜籽油、大豆油、氢化大豆油、棕榈油、坎布拉油和花生油。花生油、葵花籽油和黄油组的血清总胆固醇较低,而棕榈油和氢化大豆油组的血清总胆固醇较高(p<0.01);花生油、葵花籽油和大豆油组的血清胆固醇酯较低,而棕榈油和氢化大豆油组的血清胆固醇酯较高(p<0.01)。葵花籽油和花生油组的血清甘油三酯较低,而黄油和棕榈油组的血清甘油三酯较高(p<0.01)。各实验组血清胆固醇和磷脂之间存在显著正相关。在主动脉中,不同组的游离胆固醇水平相同,但胆固醇酯水平按以下顺序升高:坎布拉油、黄油、花生油、棕榈油、葵花籽油、菜籽油、氢化大豆油和大豆红组(p<0.01)。主动脉胆固醇酯与膳食脂肪的18:0 + 18:1比例之间存在显著相关性(r = 0.69;p<0.001)。