Fox E, Abbate E A, Leef M, Mikhail E, Said-Salah Y, Hassan A
U.S. Naval Medical Research Unit n. 3 (NAMRU-3), Le Caire, Egypte.
Med Trop (Mars). 1989 Apr-Jun;49(2):159-60.
To investigate the importance of malaria as a public health problem in Djibouti, we studied 144 febrile subjects living south of Djibouti-city in the agricultural area of Ambouli. All blood slides examined were negative for parasites. Antibodies against the merozoite stage of Plasmodium falciparum were investigated by an indirect immunofluorescence assay using serial serum dilutions. Only 9 sera reacted negatively at the titer of 50 (the chosen cut-off for positivity). Fourteen sera tested positive at a titer above 1000. Percentages of seropositive subjects and geometric mean titers increased with age. We conclude that inhabitants of Ambouli were heavily exposed to Plasmodium falciparum in the recent past. However, our data do not allow to ascertain if the malaria infections were contracted inside or outside of the national territory, since Djiboutians are frequent and extensive travelers.
为了调查疟疾作为吉布提公共卫生问题的重要性，我们研究了居住在吉布提市以南安布利农业区的144名发热患者。所有检查的血涂片均未发现寄生虫。通过间接免疫荧光试验，使用系列血清稀释液来检测抗恶性疟原虫裂殖子阶段的抗体。只有9份血清在滴度为50时呈阴性反应（选定的阳性临界值）。14份血清在滴度高于1000时检测呈阳性。血清阳性受试者的百分比和几何平均滴度随年龄增长而增加。我们得出结论，安布利的居民近期曾大量接触过恶性疟原虫。然而，由于吉布提人经常广泛出行，我们的数据无法确定疟疾感染是在该国境内还是境外感染的。
