完全植入式静脉通路装置置入的常规抗生素预防：对2154例患者的荟萃分析
Routine Antibiotic Prophylaxis for Totally Implantable Venous Access Device Placement: Meta-Analysis of 2,154 Patients.
作者信息
Johnson Evan, Babb James, Sridhar Divya
机构信息
Department of Radiology, Center for Biomedical Imaging, NYU Langone Medical Center, 660 First Avenue, New York, NY 10016.
Department of Radiology, Center for Biomedical Imaging, NYU Langone Medical Center, 660 First Avenue, New York, NY 10016.
出版信息
J Vasc Interv Radiol. 2016 Mar;27(3):339-43; quiz 344. doi: 10.1016/j.jvir.2015.11.051. Epub 2016 Jan 6.
PURPOSE
To provide a meta-analysis of currently available literature on the topic of antibiotic prophylaxis for totally implanted venous access device (TIVAD) placement.
MATERIALS AND METHODS
A systematic review of MEDLINE/PubMed was performed to identify studies that met Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria reviewing antibiotic prophylaxis in TIVAD placement. Four studies were identified that met criteria. The analysis included 2,154 patients undergoing TIVAD placement; 360 (16.7%) received antibiotic prophylaxis, and 1,794 (83.3%) received no periprocedural antibiotics.
RESULTS
In the period after TIVAD placement, 27 (1.25%) infections were identified. Of infections, five occurred in the antibiotic prophylaxis group (1.39%), and 22 occurred in the nonprophylaxis group (1.23%) with an odds ratio of 0.84 (CI = 0.29-2.35).
CONCLUSIONS
The odds ratio of infection was 0.85 with antibiotic use but one was contained within the confidence interval suggesting no significant difference in infection rate when antibiotics were used.
目的
对目前关于完全植入式静脉通路装置（TIVAD）置入时抗生素预防的文献进行荟萃分析。
材料与方法
对MEDLINE/PubMed进行系统评价，以识别符合系统评价和荟萃分析首选报告项目（PRISMA）标准的关于TIVAD置入时抗生素预防的研究。确定了四项符合标准的研究。分析纳入了2154例行TIVAD置入的患者；360例（16.7%）接受了抗生素预防，1794例（83.3%）未接受围手术期抗生素治疗。
结果
在TIVAD置入后的时间段内，发现27例（1.25%）感染。其中，抗生素预防组发生5例感染（1.39%），未预防组发生22例感染（1.23%），比值比为0.84（CI = 0.29 - 2.35）。
结论
使用抗生素时感染的比值比为0.85，但其中一个值包含在置信区间内，表明使用抗生素时感染率无显著差异。
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