de Lossada A, Rejas J
Máster en Evaluación Sanitaria y Acceso al Mercado (Farmacoeconomía), Universidad Carlos III, Getafe, Madrid, España.
Departamento de Farmacoeconomía e Investigación de Resultados en Salud, Pfizer S. L. U., Alcobendas, Madrid, España.
Semergen. 2016 Oct;42(7):431-439. doi: 10.1016/j.semerg.2015.09.003. Epub 2015 Nov 20.
Smoking has been associated with an important health risk. The aim was to analyze the health-related quality of life (HRQoL) status of the adult Spanish general population included in the National Health Survey according to its smoking status.
Data were included from National Health Survey for the year 2011-2012 with information of HRQoL status in general population over 15 years of age. Adult male and female, 18 years of age or above, were categorized into 3 exclusive groups according to their current smoking status: smokers (daily smokers of any form of tobacco, at least the previous 12 months), ex-smokers of one or more years since quitting smoking and people who have never smoked (non smokers). HRQoL was assessed with the Spanish version of the EQ-5D-5L questionnaire included into the National Health Survey.
A total of 19,604 records were analyzed: 4,723 (24.09%) smokers, 3,797 (19.37%) ex-smokers, and 11,084 (56.54%) non smokers, male and female with 18 years of age or above. Smokers showed significantly adjusted mean scores (95% CI) in utility of 0.903 (0.899-0.908) and 75.36 (74.06-76.69) in the visual analogue scale of current state of health, ex-smokers 0.924 (0.919-0.929) and 76.85 (76.67-78.07), and non smokers 0.902 (0.899-0.905) and 76.25 (75.02-77.51), P<.01 between groups in both variables.
In the Spanish general population, subjects who are ex-smokers showed better utility values and state health scores, supporting the hypothesis that quitting smoking could be associated with a discreet improvement of HRQoL.
吸烟与重大健康风险相关。本研究旨在根据吸烟状况分析纳入西班牙国民健康调查的成年普通人群的健康相关生活质量(HRQoL)状况。
数据来源于2011 - 2012年西班牙国民健康调查,其中包含15岁以上普通人群的HRQoL状况信息。18岁及以上的成年男性和女性根据其当前吸烟状况分为3个互斥组:吸烟者(任何形式烟草的每日吸烟者,至少在过去12个月内)、戒烟一年或以上的既往吸烟者以及从不吸烟的人(非吸烟者)。HRQoL通过纳入国民健康调查的西班牙文版EQ - 5D - 5L问卷进行评估。
共分析了19,604条记录:4,723名(24.09%)吸烟者、3,797名(19.37%)既往吸烟者和11,084名(56.54%)非吸烟者,年龄均在18岁及以上,包含男性和女性。吸烟者在效用方面的显著校正平均得分(95%可信区间)为0.903(0.899 - 0.908),在当前健康状况视觉模拟量表上为75.36(74.06 - 76.69);既往吸烟者分别为0.924(0.919 - 0.929)和76.85(76.67 - 78.07);非吸烟者分别为0.902(0.899 - 0.905)和76.25(75.02 - 77.51),两组在这两个变量上的P值均小于0.01。
在西班牙普通人群中,既往吸烟者显示出更好的效用值和健康状况评分,支持了戒烟可能与HRQoL的适度改善相关的假设。