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Protein components of amyloid-like kidney stones of chronic hemodialysis patients.

作者信息

Ozasa H, Suzuki T, Takahashi K, Ota K

机构信息

Kidney Center, Tokyo Women's Medical College, Japan.

出版信息

Nephron. 1989;53(3):257-60. doi: 10.1159/000185754.

DOI:10.1159/000185754
PMID:2677809
Abstract

We have examined amyloid-like kidney stones, commonly found in patients on maintenance hemodialysis. Extraction of protein from the stones and Western blot analysis were performed. beta 2-Microglobulin (beta 2MG), serum amyloid P component (SAP), lysozyme and PAS-positive substance were identified in the stones. It is suggested that calcium-mediated association of beta 2MG, lysozyme, SAP and PAS-positive substance may have an important role in the process of the formation of kidney stones in chronic hemodialysis patients.

摘要

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