Kuwabara Mitsuo, Kario Kazuomi
Division of Cardiovascular Medicine, Department of Medicine, Department of Sleep and Circadian Cardiology, Jichi Medical University School of Medicine, 3311-1, Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.
Curr Hypertens Rev. 2016;12(1):27-31. doi: 10.2174/1573402112666160114093500.
Obstructive sleep apnea (OSA) places an enormous pressure load on the cardiovascular system by inducing a temporary blood pressure (BP) surge during apnea episodes. This pressure load is regarded as a potential mechanism of development of cardiovascular diseases such as stroke. Therefore, accurate measurement of such BP surges would be valuable for the risk stratification of OSA patients. Recently we developed a new triggered nocturnal BP monitoring system (TNP) based on oxygen desaturation and have achieved success to detect BP surges with OSA. TNP would be a promising tool for assessment of cardiovascular risks in sleep apnea syndrome.
阻塞性睡眠呼吸暂停（OSA）通过在呼吸暂停发作期间引发暂时性血压（BP）飙升，给心血管系统带来巨大的压力负荷。这种压力负荷被视为诸如中风等心血管疾病发展的潜在机制。因此，准确测量此类血压飙升对于OSA患者的风险分层具有重要价值。最近，我们基于氧饱和度下降开发了一种新的触发式夜间血压监测系统（TNP），并成功检测到了与OSA相关的血压飙升。TNP可能是评估睡眠呼吸暂停综合征心血管风险的一种有前景的工具。
