用于治疗静脉血栓栓塞的抗凝剂的药理学。
Pharmacology of anticoagulants used in the treatment of venous thromboembolism.
作者信息
Nutescu Edith A, Burnett Allison, Fanikos John, Spinler Sarah, Wittkowsky Ann
机构信息
Department of Pharmacy Systems Outcomes and Policy and Center for Pharmacoepidemiology & Pharmacoeconomic Research, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
Inpatient Antithrombosis Services, University of New Mexico Hospital, University of New Mexico College of Pharmacy, Albuquerque, NM, USA.
出版信息
J Thromb Thrombolysis. 2016 Jan;41(1):15-31. doi: 10.1007/s11239-015-1314-3.
Anticoagulant drugs are the foundation of therapy for patients with VTE. While effective therapeutic agents, anticoagulants can also result in hemorrhage and other side effects. Thus, anticoagulant therapy selection should be guided by the risks, benefits and pharmacologic characteristics of each agent for each patient. Safe use of anticoagulants requires not only an in-depth knowledge of their pharmacologic properties but also a comprehensive approach to patient management and education. This paper will summarize the key pharmacologic properties of the anticoagulant agents used in the treatment of patients with VTE.
抗凝药物是VTE患者治疗的基础。尽管抗凝剂是有效的治疗药物，但也可能导致出血和其他副作用。因此，抗凝治疗的选择应根据每位患者使用每种药物的风险、益处和药理学特性来指导。安全使用抗凝剂不仅需要深入了解其药理学特性，还需要全面的患者管理和教育方法。本文将总结用于治疗VTE患者的抗凝剂的关键药理学特性。
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