Schneider Marco M, Preiss Stefan, Salzmann Gian M
Schulthess Clinic, Musculoskeletal Centre, Lengghalde 2, CH-8008, Zurich, Switzerland.
J Med Case Rep. 2016 Jan 19;10:13. doi: 10.1186/s13256-015-0796-0.
Osteochondrosis dissecans is a disorder of the subchondral bone potentially affecting the adjacent articular cartilage. There remains disunity with regard to treatment methods.
We present the case of a 21-year-old Swiss woman who presented with clinically symptomatic bilateral osteochondrosis dissecans lesions at both medial femoral condyles. She underwent sequential surgical intervention and was prospectively monitored using clinical scores and magnetic resonance imaging. Her left knee was treated with an open refixation of the osteochondrosis dissecans lesion with two 2.0 mm screws in combination with a cancellous bone graft and subchondral drilling since the cartilage of the osteochondrosis dissecans lesion was intact. On her right knee, she underwent open removal of the defective bone and cartilage, cancellous bone graft with subchondral drilling and coverage with a bilayered collagenous membrane (autologous matrix-induced chondrogenesis technique) since the cartilage of the osteochondrosis dissecans lesion was not intact. At final follow-up 12 months after surgery her Lysholm score had improved from 79 to 95 on her left side and from 74 to 78 on her right. Magnetic resonance imaging displayed good integration of the cancellous bone graft with a slight irregularity at the articular surface on her left side (magnetic resonance observation of cartilage repair tissue (MOCART) 75). The magnetic resonance imaging of her right knee depicted satisfying bony reconstitution with yet more irregularity at the joint surface (magnetic resonance observation of cartilage repair tissue 65) in comparison to her left femoral condyle.
In cases of failed conservative treatment of osteochondrosis dissecans lesions of the knee joint surgery should be taken into consideration. Considering this case, we believe that the focus should be the preservation of the cartilaginous layer whenever possible or at least replacement with high quality replacement tissue, such as autologous chondrocyte implantation.
剥脱性骨软骨炎是一种软骨下骨疾病,可能影响相邻的关节软骨。在治疗方法上仍存在分歧。
我们报告一例21岁瑞士女性,双侧股骨内侧髁出现有临床症状的剥脱性骨软骨炎病变。她接受了序贯手术干预,并通过临床评分和磁共振成像进行前瞻性监测。由于剥脱性骨软骨炎病变的软骨完整,她的左膝采用开放复位,用两枚2.0毫米螺钉固定剥脱性骨软骨炎病变,并结合松质骨移植和软骨下钻孔。在她的右膝,由于剥脱性骨软骨炎病变的软骨不完整,她接受了开放切除有缺陷的骨和软骨、松质骨移植并进行软骨下钻孔,并用双层胶原膜覆盖(自体基质诱导软骨形成技术)。术后12个月的最终随访中,她左侧的Lysholm评分从79分提高到95分,右侧从74分提高到78分。磁共振成像显示左侧松质骨移植融合良好,关节面有轻微不规则(软骨修复组织磁共振观察(MOCART)评分为75)。与左侧股骨髁相比,她右膝的磁共振成像显示骨重建良好,但关节面更不规则(软骨修复组织磁共振观察评分为65)。
对于膝关节剥脱性骨软骨炎病变保守治疗失败的病例,应考虑手术治疗。考虑到该病例,我们认为应尽可能保留软骨层,或至少用高质量的替代组织如自体软骨细胞植入进行替代。