Vila-Córcoles Angel, Forcadell M José, de Diego Cinta, Ochoa-Gondar Olga, Satué Eva, Rull Baltasar, Barnes Luis, Jariod Manel
Rev Esp Salud Publica. 2015 Nov-Dec;89(6):597-605. doi: 10.4321/S1135-57272015000600007.
Population-based data available about the epidemiology of acute myocardial infarction is limited. This study investigated incidence and mortality from infarction among the general population over 60 years in Tarragona.
Cohort study that included 27,204 individuals ≥60 years assigned to nine Primary Care Centers in the Tarragones county (Catalonia, Spain), who were prospectively followed between 01/12/2008 and 30/11/2011. During follow-up, all presumptive episodes of infarction were recruited among cohort members, but only confirmed cases (electrocardiogram and biomarkers confirmation) were included.
There were an amount of 359 confirmed episodes of infarction, which means a global incidence rate of 475 episodes per 100,000 person-years (95% CI: 428-527). Incidence was 681 in men and 311in women (p<0.001). According to age, incidence was 277 in 60-69, 632 in 70-79 and 690 per 100,000 in ≥80 years (p<0.001). Incidence was 2,844 cases per 100,000 person-years among those persons whom had history of prior coronary artery disease. Overall 30-day mortality rate was 15.3%, in male 14.9% and in female 16.0% (p=0.776).
Incidence was 2.2 times higher in men than in woman and increased considerable by age. It was greater among patients with prior history of coronary artery disease. Mortality was slightly lower in men than in women.
关于急性心肌梗死流行病学的基于人群的数据有限。本研究调查了塔拉戈纳60岁以上普通人群中梗死的发病率和死亡率。
队列研究纳入了塔拉戈纳斯县（西班牙加泰罗尼亚）9个初级保健中心的27204名60岁及以上个体，于2008年12月1日至2011年11月30日进行前瞻性随访。随访期间，队列成员中所有疑似梗死发作均被纳入，但仅纳入确诊病例（心电图和生物标志物确诊）。
共有359例确诊梗死发作，这意味着总体发病率为每10万人年475例（95%可信区间：428 - 527）。男性发病率为681例，女性为311例（p<0.001）。按年龄划分，60 - 69岁发病率为277例，70 - 79岁为632例，80岁及以上为每10万人690例（p<0.001）。有冠心病病史者发病率为每10万人年2844例。总体30天死亡率为15.3%，男性为14.9%，女性为16.0%（p = 0.776）。
男性发病率比女性高2.2倍，且随年龄显著增加。有冠心病病史的患者发病率更高。男性死亡率略低于女性。
