Butler D P, Sweet J B
Oral Surg Oral Med Oral Pathol. 1977 Jul;44(1):14-20. doi: 10.1016/0030-4220(77)90235-3.
Four hundred twenty-two mandibular third molars were extracted in 211 patients. After extraction, one half of the surgical sites were subjected to a 175 ml. lavage with normal saline solution, and the other half received a lavage of less than 25 ml. of normal saline solution. Comparisons revealed the following: 1. The overall incidence of localized osteitis was 8.3 per cent (thirty-five of 422 sites). 2. Localized osteitis occurred at twelve of 211 (5.7 per cent) sites which were subjected to the higher-volume lavage. 3. Localized osteitis occurred at twenty-three of 211 (10.9 per cent) sites which were subjected to minimal lavage. 4. The incidence of localized osteitis was determined in the various age groups as follows: ages 15 to 20, 5.0 per cent; ages 21 to 35, 10.4 per cent; ages 26 to 30, 14.7 per cent. 5. Localized osteitis occurred at eight of 175 (4.5 per cent) partial-impaction sites, whereas it occurred at twenty-seven of 246 (11 per cent) complete-impaction sites. 6. The incidence of localized osteitis at extraction sites in female patients taking oral contraceptives was 19.4 per cent (seven of thirty-six sites). 7. Postoperative infection occurred at seven of 422 extraction sites (1.4 per cent); six of these occurred at sites which were subjected to minimal lavage. These results indicate that the use of a 175 ml. lavage with normal saline solution after extraction of mandibular third molars will significantly reduce the incidence of localized osteitis to approximately one half of that observed when only a minimal-volume lavage is used. The results also suggest that age, type of impaction, and whether the patient is taking oral contraceptives are all important factors to be considered in the incidence of localized osteitis.
对211例患者的422颗下颌第三磨牙进行了拔除。拔牙后,一半的手术创口用175毫升生理盐水冲洗,另一半接受少于25毫升生理盐水的冲洗。比较结果如下:1.局限性骨炎的总体发生率为8.3%(422个创口中有35个)。2.在接受较大容量冲洗的211个创口中有12个(5.7%)发生局限性骨炎。3.在接受少量冲洗的211个创口中有23个(10.9%)发生局限性骨炎。4.局限性骨炎的发生率在不同年龄组中如下:15至20岁,5.0%;21至35岁,10.4%;26至30岁,14.7%。5.在175个部分阻生创口中有8个(4.5%)发生局限性骨炎,而在246个完全阻生创口中有27个(11%)发生。6.服用口服避孕药的女性患者拔牙创口处局限性骨炎的发生率为19.4%(36个创口中有7个)。7.422个拔牙创口中有7个(1.4%)发生术后感染;其中6个发生在接受少量冲洗的创口处。这些结果表明,下颌第三磨牙拔除后用175毫升生理盐水冲洗将显著降低局限性骨炎的发生率,降至仅使用少量冲洗时观察到的发生率的约一半。结果还表明,年龄、阻生类型以及患者是否服用口服避孕药都是局限性骨炎发生率中需要考虑的重要因素。