Khodyrev A P, Beliakov V D
Zh Mikrobiol Epidemiol Immunobiol. 1989 Jun(6):34-8.
This work presents the data on the complex evaluation of the population of group A streptococci, studied at each of four phases (reservation, epidemic transformation, epidemic spread, reservational transformation) of the course of the epidemic process of streptococcal infection of the respiratory tracts (tonsillitis) in an organized group of adults. The characterization of the phases of the infective agent in accordance with the level of the carrier state, the size of streptococcal foci and the virulence of streptococci is given. Thus, the study shows that the heterogeneity of group A streptococci with respect to their virulence reaches its maximum level at the phases of reservation and epidemic spread and its minimum level at the phases of epidemic and reservational transformation. The size of streptococcal foci in carriers and the virulence of streptococci isolated from them are the inter-related unidirectional signs of the population of the infective agent and, at the same time, the main factors responsible for the phase character of the epidemic process and the morbidity level in tonsillitis.
本研究呈现了对A组链球菌群体进行综合评估的数据，该评估是在一组有组织的成年人呼吸道（扁桃体炎）链球菌感染流行过程的四个阶段（留存、流行转变、流行传播、留存转变）中的每个阶段进行的。文中给出了根据带菌状态水平、链球菌病灶大小和链球菌毒力对感染因子各阶段的特征描述。因此，研究表明，A组链球菌在毒力方面的异质性在留存和流行传播阶段达到最高水平，而在流行和留存转变阶段达到最低水平。带菌者中链球菌病灶的大小以及从他们身上分离出的链球菌的毒力是感染因子群体相互关联的单向指标，同时也是决定流行过程阶段特征和扁桃体炎发病率水平的主要因素。
