University of Toronto, Toronto, ON, Canada
N Engl J Med. 2016 Jan 21;374(3):e3. doi: 10.1056/NEJMicm1505596.
A 56-year-old man presented to the emergency department with a 5-hour history of throat swelling and pain and difficulty breathing that was exacerbated by supine positioning; he had not had any obvious antecedent trauma. His medical history included prostate cancer, hypertension, hyperlipidemia, deep-vein thrombosis, and stroke. Medications included warfarin (presumably for deep-vein thrombosis), antihypertensive agents, and a statin. He was afebrile, and the physical examination was notable for minor swelling of the posterior oropharynx. Laboratory studies revealed a normal white-cell count, an international normalized ratio of more than 11, a prothrombin time of more than 120 seconds, and an activated . . .
一位 56 岁男性因咽喉肿胀和疼痛并伴有呼吸困难就诊于急诊科，该症状在仰卧位时加重，且患者无明显外伤史。他的既往病史包括前列腺癌、高血压、高脂血症、深静脉血栓形成和中风。他正在服用华法林（可能用于治疗深静脉血栓形成）、降压药和他汀类药物。他无发热，体格检查仅发现后口咽轻微肿胀。实验室检查显示白细胞计数正常，国际标准化比值大于 11，凝血酶原时间大于 120 秒，活化部分凝血活酶时间大于 65 秒。
