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[一例男性不育患者的卡塔格内综合征病例]

[A Case of Kartagener's Syndrome in Infertile Male Patients].

作者信息

Mori Kohei, Yumura Yasushi, Takeshima Teppei, Yamanaka Hiroyuki, Kuroda Shinnosuke, Sanjyo Hiroyuki, Yasuda Kengo, Noguchi Kazumi

机构信息

The Department of Reproductive Medicine Center, Yokohama City University Medical Center.

出版信息

Hinyokika Kiyo. 2015 Dec;61(12):509-13.

Abstract

The patient was a 33-year-old man attending the infertility clinic with primary infertility of 3 years duration. The semen examination showed oligozoospermia and suspected primary male infertility. He had a history of chronic sinusitis and respiratory disease. His chest X-ray showed dextrocardia. Abnormality of the ultrastructure of the cilia of the tract epithelium was found by electron microscopy, and further examination revealed bronchoectasis. We gave him a diagnosis of Kartagener syndrome from these findings. Kartagener syndrome consists of bronchiectasis, sinusitis and situs inversus and is considered a form of primary ciliary dyskinesia (PCD). PCD is also a cause of motor impairment of sperm flagella. This case had successful in-vitro fertilization pregnancy with spermatozoa from the patient.

摘要

该患者为一名33岁男性,因原发性不孕3年就诊于不孕不育诊所。精液检查显示少精子症,怀疑为原发性男性不育。他有慢性鼻窦炎和呼吸系统疾病史。胸部X线显示右位心。通过电子显微镜检查发现呼吸道上皮纤毛超微结构异常,进一步检查发现支气管扩张。根据这些发现,我们诊断他为卡塔格内综合征。卡塔格内综合征包括支气管扩张、鼻窦炎和内脏转位,被认为是原发性纤毛运动障碍(PCD)的一种形式。PCD也是精子鞭毛运动障碍的一个原因。该病例通过使用患者的精子成功实现了体外受精妊娠。

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